VYVANSE 50 MG CHEWABLE TABLET
FDA nonproprietary name: lisdexamfetamine dimesylate
For 30 tablets
Pharmacies pay
$370.75 filed
30 × $12.35835 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$386.40 filed
30 × $12.8801 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.0× estimated
Medicare paid about what pharmacies pay.
Part D averages every strength and form sold under “Vyvanse” / “Lisdexamfetamine Dimesylate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$431.36 estimated
$370.75 + $55.61 (15%) + $5.00 fee per fill = $431.36
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
VYVANSE 50 MG CHEWABLE TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as lisdexamfetamine dimesylate, under the trade name “Vyvanse”.
FDA gives its dosage form as tablet, chewable and its route as oral.
The labeler, the company named on the label, is Takeda Pharmaceuticals America, Inc.
FDA’s Established Pharmacologic Class for it is Central Nervous System Stimulant.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 59417-0119-01.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $370.75 for 30 tablets (30 × $12.35835 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $3.64862 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · Why 30 tablets · NADAC explanation codes
The NDC
- 59417-0119-01 · Takeda Pharmaceuticals America, Inc. · $12.35835 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
25 other products in the NADAC file share the FDA nonproprietary name lisdexamfetamine dimesylate with VYVANSE 50 MG CHEWABLE TABLET. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| LISDEXAMFETAMINE 10 MG CAPSULE | $2.624 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 10 MG TB CHEW | $3.73818 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 20 MG CAPSULE | $2.43711 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 20 MG TB CHEW | $4.33791 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 30 MG CAPSULE | $2.70088 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 30 MG TB CHEW | $3.29147 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 40 MG CAPSULE | $2.60126 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 40 MG TB CHEW | $3.98071 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 50 MG CAPSULE | $2.63983 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 50 MG TB CHEW | $3.64862 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 60 MG CAPSULE | $2.67291 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 60 MG TB CHEW | $3.64601 per EA filed | $6.94023 per EA filed |
| LISDEXAMFETAMINE 70 MG CAPSULE | $2.67532 per EA filed | $6.94023 per EA filed |
| VYVANSE 10 MG CAPSULE | $12.3494 per EA filed | $12.8801 per EA filed |
| VYVANSE 10 MG CHEWABLE TABLET | $12.35842 per EA filed | $12.8801 per EA filed |
| VYVANSE 20 MG CAPSULE | $12.34801 per EA filed | $12.8801 per EA filed |
| VYVANSE 20 MG CHEWABLE TABLET | $12.35039 per EA filed | $12.8801 per EA filed |
| VYVANSE 30 MG CAPSULE | $12.34562 per EA filed | $12.8801 per EA filed |
| VYVANSE 30 MG CHEWABLE TABLET | $12.34907 per EA filed | $12.8801 per EA filed |
| VYVANSE 40 MG CAPSULE | $12.34964 per EA filed | $12.8801 per EA filed |
| VYVANSE 40 MG CHEWABLE TABLET | $12.3567 per EA filed | $12.8801 per EA filed |
| VYVANSE 50 MG CAPSULE | $12.34718 per EA filed | $12.8801 per EA filed |
| VYVANSE 50 MG CHEWABLE TABLET this page | $12.35835 per EA filed | $12.8801 per EA filed |
| VYVANSE 60 MG CHEWABLE TABLET | $12.36499 per EA filed | $12.8801 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $12.35835 per EA filed.
Of the 203 other products in FDA’s Central Nervous System Stimulant class priced per EA, 43 have a higher middle NADAC price and 160 a lower one. The one in the middle is LISDEXAMFETAMINE 20 MG TB CHEW, at $4.33791 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $386.40 for 30 tablets, at an average of $12.8801 per EA in 2024 (2024-01-01 to 2024-12-31) for “Vyvanse” and “Lisdexamfetamine Dimesylate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 212,410 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: LISDEXAMFETAMINE 50 MG TB CHEW. Ask your pharmacist or prescriber; do not switch on your own.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for VYVANSE 50 MG CHEWABLE TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Vyvanse / Lisdexamfetamine Dimesylate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
Related pages
Its pharmacologic class
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