OpenBilldrug price receipt

NADAC week of 2026-10-14

XULTOPHY 100 UNIT-3.6 MG/ML PEN

FDA nonproprietary name: insulin degludec and liraglutide

For 15 mL

Pharmacies pay

$1,288.28 filed

15 × $85.88557 per ML

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$1,223.50 filed

15 × $81.56641 per ML, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

0.95× estimated

Medicare paid 5% less than pharmacies pay.

Part D averages every strength and form sold under “Xultophy 100-3.6” / “Insulin Degludec/Liraglutide” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$1,486.52 estimated

$1,288.28 + $193.24 (15%) + $5.00 fee per fill = $1,486.52

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

XULTOPHY 100 UNIT-3.6 MG/ML PEN is how the CMS NADAC file names this product. The FDA NDC Directory lists it as insulin degludec and liraglutide, under the trade name “Xultophy 100/3.6”.

FDA gives its dosage form as injection, solution and its route as subcutaneous.

The labeler, the company named on the label, is Novo Nordisk.

FDA lists it under 2 Established Pharmacologic Classes: GLP-1 Receptor Agonist and Insulin Analog.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00169-2911-15.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $1,288.28 for 15 mL (15 × $85.88557 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

The NDC

Compared with its class

Its NADAC price is $85.88557 per ML filed.

Of the 39 other products in FDA’s GLP-1 Receptor Agonist class priced per ML, 35 have a higher middle NADAC price and 4 a lower one. The one in the middle is WEGOVY 1.7 MG/0.75 ML PEN, at $435.55769 per ML filed (eff. 2026-09-23).

Of the 56 other products in FDA’s Insulin Analog class priced per ML, 2 have a higher middle NADAC price and 54 a lower one. The one in the middle is TRESIBA FLEXTOUCH 100 UNIT/ML, at $9.03577 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $1,223.50 for 15 mL, at an average of $81.56641 per ML in 2024 (2024-01-01 to 2024-12-31) for “Xultophy 100-3.6” and “Insulin Degludec/Liraglutide”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 57,197 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for XULTOPHY 100 UNIT-3.6 MG/ML PEN labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Xultophy 100-3.6 / Insulin Degludec/Liraglutide: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on brand name.
Why does this page start at 15 mL?
NADAC prices this product per ML. The FDA NDC Directory’s package description gives 15 mL in one package for this product’s NDC (“5 SYRINGE, PLASTIC in 1 CARTON (0169-2911-15) / 3 mL in 1 SYRINGE, PLASTIC”), so the card starts at one package: 15 ML. Change it to match your prescription.