XULTOPHY 100 UNIT-3.6 MG/ML PEN
FDA nonproprietary name: insulin degludec and liraglutide
For 15 mL
Pharmacies pay
$1,288.28 filed
15 × $85.88557 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$1,223.50 filed
15 × $81.56641 per ML, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.95× estimated
Medicare paid 5% less than pharmacies pay.
Part D averages every strength and form sold under “Xultophy 100-3.6” / “Insulin Degludec/Liraglutide” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$1,486.52 estimated
$1,288.28 + $193.24 (15%) + $5.00 fee per fill = $1,486.52
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
XULTOPHY 100 UNIT-3.6 MG/ML PEN is how the CMS NADAC file names this product. The FDA NDC Directory lists it as insulin degludec and liraglutide, under the trade name “Xultophy 100/3.6”.
FDA gives its dosage form as injection, solution and its route as subcutaneous.
The labeler, the company named on the label, is Novo Nordisk.
FDA lists it under 2 Established Pharmacologic Classes: GLP-1 Receptor Agonist and Insulin Analog.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00169-2911-15.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1,288.28 for 15 mL (15 × $85.88557 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The NDC
- 00169-2911-15 · Novo Nordisk · $85.88557 per ML · eff. 2026-09-23 filed
Compared with its class
Its NADAC price is $85.88557 per ML filed.
Of the 39 other products in FDA’s GLP-1 Receptor Agonist class priced per ML, 35 have a higher middle NADAC price and 4 a lower one. The one in the middle is WEGOVY 1.7 MG/0.75 ML PEN, at $435.55769 per ML filed (eff. 2026-09-23).
Of the 56 other products in FDA’s Insulin Analog class priced per ML, 2 have a higher middle NADAC price and 54 a lower one. The one in the middle is TRESIBA FLEXTOUCH 100 UNIT/ML, at $9.03577 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $1,223.50 for 15 mL, at an average of $81.56641 per ML in 2024 (2024-01-01 to 2024-12-31) for “Xultophy 100-3.6” and “Insulin Degludec/Liraglutide”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 57,197 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 15 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 15 mL; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for XULTOPHY 100 UNIT-3.6 MG/ML PEN labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Xultophy 100-3.6 / Insulin Degludec/Liraglutide: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on brand name.
- Why does this page start at 15 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 15 mL in one package for this product’s NDC (“5 SYRINGE, PLASTIC in 1 CARTON (0169-2911-15) / 3 mL in 1 SYRINGE, PLASTIC”), so the card starts at one package: 15 ML. Change it to match your prescription.
Related pages
Its pharmacologic classes
Related in the same class
- SOLIQUA 100 UNIT-33 MCG/ML PEN
- LANTUS SOLOSTAR 100 UNIT/ML
- MOUNJARO 10 MG/0.5 ML PEN
- TRULICITY 0.75 MG/0.5 ML PEN
- NOVOLOG 100 UNIT/ML FLEXPEN