Why is the comparison with Medicare for AMIODARONE HCL 400 MG TABLET labelled estimated?

Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Amiodarone HCl* / Amiodarone HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes ORAL point at this name (27 of the 29 the name join matched); NDCs of another route or with no known FDA route do not. 2 of the 27 NDCs that point at this name are not listed in the FDA NDC Directory as packages of their own; their route was taken from FDA's record for the same product (labeler and product code). 27 of 29 NADAC NDCs joined to this name are priced per EA (2 per ML): CMS's average mixes those units.

AMIODARONE HCL 400 MG TABLET

For 30 tablets

Pharmacies pay

$14.99 filed

30 × $0.49957 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$12.49 filed

30 × $0.41637 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

The spread

0.83× estimated

Medicare paid 17% less than pharmacies pay.

Part D averages every strength and form sold under “Amiodarone HCl*” / “Amiodarone HCl” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$22.24 estimated

$14.99 + $2.25 (15%) + $5.00 fee per fill = $22.24

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

AMIODARONE HCL 400 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as amiodarone hydrochloride.

FDA gives its dosage form as tablet and its route as oral.

FDA lists 4 labelers (the companies named on the label) for its NDCs, among them Sun Pharmaceutical Industries, Inc., Chartwell RX, LLC and Zydus Pharmaceuticals USA Inc.

FDA’s Established Pharmacologic Class for it is Antiarrhythmic.

The NADAC file of 2026-10-14 prices it under 4 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $14.99 for 30 tablets (30 × $0.49957 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

What NADAC measures · Why 30 tablets · NADAC explanation codes

All 4 NDCs

51672-4057-06 · Sun Pharmaceutical Industries, Inc. · $0.49957 per EA · eff. 2026-09-23 filed
62135-0578-30 · Chartwell RX, LLC · $0.49957 per EA · eff. 2026-09-23 filed
68382-0298-06 · Zydus Pharmaceuticals USA Inc. · $0.49957 per EA · eff. 2026-09-23 filed
72888-0061-30 · Advagen Pharma Limited · $0.49957 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

5 other products in the NADAC file share the FDA nonproprietary name amiodarone hydrochloride with AMIODARONE HCL 400 MG TABLET.

Product	Pharmacies pay per unit	Medicare per unit
AMIODARONE 150 MG/3 ML VIAL generic · injection, solution	$0.52115 per ML filed eff. 2026-07-22	$0.64 per ML derived Part B limit 2026 Q4
AMIODARONE HCL 100 MG TABLET generic · tablet	$0.37584 per EA filed eff. 2026-09-23	$0.41637 per EA filed Part D 2024 average
AMIODARONE HCL 200 MG TABLET generic · tablet	$0.12179 per EA filed eff. 2026-09-23	$0.41637 per EA filed Part D 2024 average
AMIODARONE HCL 400 MG TABLET this page generic · tablet	$0.49957 per EA filed eff. 2026-09-23	$0.41637 per EA filed Part D 2024 average
PACERONE 100 MG TABLET brand · tablet	$0.7762 per EA filed eff. 2026-06-17	$1.98836 per EA filed Part D 2024 average
PACERONE 200 MG TABLET brand · tablet	$0.12488 per EA filed eff. 2025-11-19	$1.98836 per EA filed Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. between 2025-11-19 and 2026-09-23 (4 dates) · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)

Compared with its class

The middle of its 4 NDCs’ NADAC prices is $0.49957 per EA filed.

Of the 43 other products in FDA’s Antiarrhythmic class priced per EA, 20 have a higher middle NADAC price and 23 a lower one. The one in the middle is MEXILETINE 250 MG CAPSULE, at $0.38721 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $12.49 for 30 tablets, at an average of $0.41637 per EA in 2024 (2024-01-01 to 2024-12-31) for “Amiodarone HCl*” and “Amiodarone HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 3,102,724 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.

Questions

Why is the comparison with Medicare for AMIODARONE HCL 400 MG TABLET labelled estimated?: Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Amiodarone HCl* / Amiodarone HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes ORAL point at this name (27 of the 29 the name join matched); NDCs of another route or with no known FDA route do not. 2 of the 27 NDCs that point at this name are not listed in the FDA NDC Directory as packages of their own; their route was taken from FDA's record for the same product (labeler and product code). 27 of 29 NADAC NDCs joined to this name are priced per EA (2 per ML): CMS's average mixes those units.

Its pharmacologic class

Antiarrhythmic 76 products