BARACLUDE 0.5 MG TABLET
FDA nonproprietary name: entecavir
For 30 tablets
Pharmacies pay
$1,325.60 filed
30 × $44.18654 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-11-19 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$938.49 filed
30 × $31.28299 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.71× estimated
Medicare paid 29% less than pharmacies pay.
Part D averages every strength and form sold under “Baraclude” / “Entecavir” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2025-11-19 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$1,529.44 estimated
$1,325.60 + $198.84 (15%) + $5.00 fee per fill = $1,529.44
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2025-11-19 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
BARACLUDE 0.5 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as entecavir, under the trade name “BARACLUDE”.
FDA gives its dosage form as tablet, film coated and its route as oral.
The labeler, the company named on the label, is E.R. Squibb & Sons, L.L.C.
FDA’s Established Pharmacologic Class for it is Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00003-1611-12.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1,325.60 for 30 tablets (30 × $44.18654 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2025-11-19. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 4, carried forward from the previous file.
This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2025-11-19. The file is new; the price is not.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $0.21857 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · Why 30 tablets · NADAC explanation codes · Carried-forward prices
The NDC
- 00003-1611-12 · E.R. Squibb & Sons, L.L.C. · $44.18654 per EA · eff. 2025-11-19 filed carried forward
Other strengths, forms and brands
2 other products in the NADAC file share the FDA nonproprietary name entecavir with BARACLUDE 0.5 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| BARACLUDE 0.5 MG TABLET this page | $44.18654 per EA filed | $31.28299 per EA filed |
| ENTECAVIR 0.5 MG TABLET | $0.21857 per EA filed | We don’t know yet |
| ENTECAVIR 1 MG TABLET | $0.36844 per EA filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-11-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $44.18654 per EA filed.
Of the 28 other products in FDA’s Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor class priced per EA, 15 have a higher middle NADAC price and 13 a lower one. The one in the middle is VEMLIDY 25 MG TABLET, at $51.98384 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-11-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $938.49 for 30 tablets, at an average of $31.28299 per EA in 2024 (2024-01-01 to 2024-12-31) for “Baraclude” and “Entecavir”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 1,512 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: ENTECAVIR 0.5 MG TABLET. Ask your pharmacist or prescriber; do not switch on your own.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for BARACLUDE 0.5 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Baraclude / Entecavir: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
Related pages
Its pharmacologic class
Related in the same class
- DESCOVY 120-15 MG TABLET
- DOVATO 50-300 MG TABLET
- TRIUMEQ 600-50-300 MG TABLET
- VEMLIDY 25 MG TABLET
- SYMTUZA 800-150-200-10 MG TAB