SYMTUZA 800-150-200-10 MG TAB
FDA nonproprietary name: darunavir, cobicistat, emtricitabine, and tenofovir alafenamide
For 30 tablets
Pharmacies pay
$4,586.02 filed
30 × $152.86728 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$4,646.33 filed
30 × $154.87775 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.0× estimated
Medicare paid about what pharmacies pay.
Part D averages every strength and form sold under “Symtuza” / “Darunavir/Cob/Emtri/Tenof Alaf” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$5,278.92 estimated
$4,586.02 + $687.90 (15%) + $5.00 fee per fill = $5,278.92
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
SYMTUZA 800-150-200-10 MG TAB is how the CMS NADAC file names this product. The FDA NDC Directory lists it as darunavir, cobicistat, emtricitabine, and tenofovir alafenamide, under the trade name “Symtuza”.
FDA gives its dosage form as tablet, film coated and its route as oral.
The labeler, the company named on the label, is Janssen Products LP.
FDA lists it under 4 Established Pharmacologic Classes: Cytochrome P450 3A Inhibitor, Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor, Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor and Protease Inhibitor.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 59676-0800-30.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $4,586.02 for 30 tablets (30 × $152.86728 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The NDC
- 59676-0800-30 · Janssen Products LP · $152.86728 per EA · eff. 2026-09-23 filed
Compared with its class
Its NADAC price is $152.86728 per EA filed.
Of the 7 other products in FDA’s Cytochrome P450 3A Inhibitor class priced per EA, 0 have a higher middle NADAC price and 7 a lower one. The one in the middle is EVOTAZ 300 MG-150 MG TABLET, at $52.0479 per EA filed (eff. 2026-09-23).
Of the 28 other products in FDA’s Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor class priced per EA, 0 have a higher middle NADAC price and 28 a lower one. The one in the middle is BARACLUDE 0.5 MG TABLET, at $44.18654 per EA filed (eff. 2025-11-19).
Of the 28 other products in FDA’s Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor class priced per EA, 0 have a higher middle NADAC price and 28 a lower one. The one in the middle is VIREAD 300 MG TABLET, at $40.6865 per EA filed (eff. 2026-09-23).
Of the 11 other products in FDA’s Protease Inhibitor class priced per EA, 0 have a higher middle NADAC price and 11 a lower one. The one in the middle is LOPINAVIR-RITONAVR 200-50 MG TB, at $4.46491 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-11-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $4,646.33 for 30 tablets, at an average of $154.87775 per EA in 2024 (2024-01-01 to 2024-12-31) for “Symtuza” and “Darunavir/Cob/Emtri/Tenof Alaf”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 91,050 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for SYMTUZA 800-150-200-10 MG TAB labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Symtuza / Darunavir/Cob/Emtri/Tenof Alaf: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
Related pages
Its pharmacologic classes
- Cytochrome P450 3A Inhibitor
- Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor
- Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
- Protease Inhibitor
Related in the same class
- GENVOYA TABLET
- STRIBILD TABLET
- DESCOVY 120-15 MG TABLET
- DOVATO 50-300 MG TABLET
- TRIUMEQ 600-50-300 MG TABLET