BUPRENORPHINE-NALOXONE 4-1 MG SL FILM
For 30 films
Pharmacies pay
$77.29 filed
30 × $2.57624 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$78.76 filed
30 × $2.62528 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.0× estimated
Medicare paid about what pharmacies pay.
Part D averages every strength and form sold under “Buprenorphine-Naloxone” / “Buprenorphine HCl/Naloxone HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$93.88 estimated
$77.29 + $11.59 (15%) + $5.00 fee per fill = $93.88
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
BUPRENORPHINE-NALOXONE 4-1 MG SL FILM is how the CMS NADAC file names this product. The FDA NDC Directory lists it as buprenorphine and naloxone, under the trade name “Buprenorphine and Naloxone Sublingual Film”.
FDA gives its dosage form as “film” and “film, soluble” and its route as buccal; sublingual.
FDA lists 4 labelers (the companies named on the label) for its NDCs, among them Mylan Pharmaceuticals Inc., Dr.Reddys Laboratories Inc and Alvogen Inc.
FDA lists it under 2 Established Pharmacologic Classes: Opioid Antagonist and Partial Opioid Agonist.
The NADAC file of 2026-10-14 prices it under 8 NDCs (National Drug Codes); the FDA directory lists 4 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $77.29 for 30 films (30 × $2.57624 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · NADAC explanation codes
The 4 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Alvogen Inc. | 1 | $2.57624 per EA filed |
| Dr.Reddys Laboratories Inc | 1 | $2.57624 per EA filed |
| INGENUS PHARMACEUTICALS, LLC | 1 | $2.57624 per EA filed |
| Mylan Pharmaceuticals Inc. | 1 | $2.57624 per EA filed |
| Not listed as a package in the FDA directory | 4 | $2.57624 per EA filed |
All 8 NDCs, with labeler and price
- 00378-8766-16 · not listed as a package in the FDA directory · $2.57624 per EA · eff. 2026-09-23 filed
- 00378-8766-93 · Mylan Pharmaceuticals Inc. · $2.57624 per EA · eff. 2026-09-23 filed
- 43598-0580-01 · not listed as a package in the FDA directory · $2.57624 per EA · eff. 2026-09-23 filed
- 43598-0580-30 · Dr.Reddys Laboratories Inc · $2.57624 per EA · eff. 2026-09-23 filed
- 47781-0356-03 · Alvogen Inc. · $2.57624 per EA · eff. 2026-09-23 filed
- 47781-0356-11 · not listed as a package in the FDA directory · $2.57624 per EA · eff. 2026-09-23 filed
- 50742-0398-01 · not listed as a package in the FDA directory · $2.57624 per EA · eff. 2026-09-23 filed
- 50742-0398-30 · INGENUS PHARMACEUTICALS, LLC · $2.57624 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share the FDA nonproprietary name buprenorphine and naloxone with BUPRENORPHINE-NALOXONE 4-1 MG SL FILM.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM | $1.38554 per EA filed | $2.62528 per EA filed |
| BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET | $0.52138 per EA filed | $2.62528 per EA filed |
| BUPRENORPHINE-NALOXONE 4-1 MG SL FILM this page | $2.57624 per EA filed | $2.62528 per EA filed |
| BUPRENORPHINE-NALOXONE 8-2 MG SL FILM | $1.98226 per EA filed | $2.62528 per EA filed |
| BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET | $0.66282 per EA filed | $2.62528 per EA filed |
| BUPRENORPHINE-NALOXONE 12-3 MG SL FILM | $4.48557 per EA filed | $2.62528 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 8 NDCs’ NADAC prices is $2.57624 per EA filed.
Of the 30 other products in FDA’s Opioid Antagonist class priced per EA, 24 have a higher middle NADAC price and 6 a lower one. The one in the middle is MOVANTIK 12.5 MG TABLET, at $14.59872 per EA filed (eff. 2026-09-23).
Of the 34 other products in FDA’s Partial Opioid Agonist class priced per EA, 28 have a higher middle NADAC price and 6 a lower one. The one in the middle is BELBUCA 300 MCG FILM, at $11.85628 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $78.76 for 30 films, at an average of $2.62528 per EA in 2024 (2024-01-01 to 2024-12-31) for “Buprenorphine-Naloxone” and “Buprenorphine HCl/Naloxone HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 1,625,314 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 films? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Buprenorphine-Naloxone / Buprenorphine HCl/Naloxone HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
- Why does this page start at 30 films?
- NADAC prices this product per EA, and the FDA NDC Directory lists 4 of its 8 NDCs (it does not list the other 4) as a film taken under the tongue or against the cheek (dosage forms “FILM”, “FILM, SOLUBLE”, route “BUCCAL; SUBLINGUAL”), so one EA is one film. OpenBill counts a tablet or film taken under the tongue or against the cheek as an oral solid, like one that is swallowed. The card starts at 30 films, a common one-month supply of a once-a-day medicine; change it to match your prescription.
Related pages
Its pharmacologic classes
Related in the same class
- SUBOXONE 12 MG-3 MG SL FILM
- ZUBSOLV 0.7-0.18 MG TABLET SL
- NALOXONE 0.4 MG/ML VIAL
- NALTREXONE 50 MG TABLET
- MOVANTIK 12.5 MG TABLET