NALOXONE 0.4 MG/ML VIAL
For 1 mL
Pharmacies pay
$3.82 filed
1 × $3.82425 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$30.90 filed
1 × $30.89639 per ML, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
8.1× estimated
Medicare paid 8.1× what pharmacies pay.
Part D averages every strength and form sold under “Naloxone HCl*” / “Naloxone HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$9.39 estimated
$3.82 + $0.57 (15%) + $5.00 fee per fill = $9.39
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
NALOXONE 0.4 MG/ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as naloxone hydrochloride.
FDA gives its dosage form as injection, solution and its route as intramuscular; intravenous; subcutaneous.
FDA lists 6 labelers (the companies named on the label) for its NDCs, among them Hospira, Inc., Baxter Healthcare Corporation and Mylan Institutional LLC.
FDA’s Established Pharmacologic Class for it is Opioid Antagonist.
The NADAC file of 2026-10-14 prices it under 7 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $3.82 for 1 mL (1 × $3.82425 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The 6 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Lifestar Pharma LLC | 2 | $3.82425 per ML filed |
| Baxter Healthcare Corporation | 1 | $3.82425 per ML filed |
| Hospira, Inc. | 1 | $3.82425 per ML filed |
| Mylan Institutional LLC | 1 | $3.82425 per ML filed |
| NorthStar RxLLC | 1 | $3.82425 per ML filed |
| Somerset Therapeutics, LLC | 1 | $3.82425 per ML filed |
All 7 NDCs, with labeler and price
- 00409-1215-01 · Hospira, Inc. · $3.82425 per ML · eff. 2026-09-23 filed
- 36000-0308-10 · Baxter Healthcare Corporation · $3.82425 per ML · eff. 2026-09-23 filed
- 67457-0292-02 · Mylan Institutional LLC · $3.82425 per ML · eff. 2026-09-23 filed
- 70069-0071-10 · Somerset Therapeutics, LLC · $3.82425 per ML · eff. 2026-09-23 filed
- 70756-0658-10 · Lifestar Pharma LLC · $3.82425 per ML · eff. 2026-09-23 filed
- 70756-0850-10 · Lifestar Pharma LLC · $3.82425 per ML · eff. 2026-09-23 filed
- 72603-0590-10 · NorthStar RxLLC · $3.82425 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share the FDA nonproprietary name naloxone hydrochloride with NALOXONE 0.4 MG/ML VIAL.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| FT NALOXONE HCL 4 MG NASAL SPR | $17.17734 per EA filed | We don’t know yet |
| GNP NALOXONE HCL 4 MG NASAL SP | $17.17734 per EA filed | We don’t know yet |
| NALOXONE 0.4 MG/ML VIAL this page | $3.82425 per ML filed | $30.89639 per ML filed |
| NALOXONE 2 MG/2 ML SYRINGE | $6.27129 to $12.74097 per ML filed | $30.89639 per ML filed |
| NALOXONE 4 MG/10 ML VIAL | $3.82425 per ML filed | $30.89639 per ML filed |
| NALOXONE HCL 4 MG NASAL SPRAY | $17.17734 per EA filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
Medicare Part D paid $30.90 for 1 mL, at an average of $30.89639 per ML in 2024 (2024-01-01 to 2024-12-31) for “Naloxone HCl*” and “Naloxone HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 715,410 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for NALOXONE 0.4 MG/ML VIAL labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Naloxone HCl* / Naloxone HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes INTRAMUSCULAR and INTRAVENOUS and SUBCUTANEOUS point at this name (19 of the 27 the name join matched); NDCs of another route or with no known FDA route do not. 3 of the 19 NDCs that point at this name are not listed in the FDA NDC Directory as packages of their own; their route was taken from FDA's record for the same product (labeler and product code).
- Why does this page start at 1 mL?
- NADAC prices this product per ML. In the FDA NDC Directory, 7 of this product’s NDCs are wholesale packs of identical units, so OpenBill counts one unit of each; for example, NDC 00409-1215-01 (“10 VIAL, SINGLE-DOSE in 1 CARTON (0409-1215-01) / 1 mL in 1 VIAL, SINGLE-DOSE (0409-1215-21)”) is a carton of 10 vials, 10 mL in all. So the card starts at one unit: 1 ML. Change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- BUPRENORPHINE-NALOXONE 12-3 MG SL FILM
- NALTREXONE 50 MG TABLET
- MOVANTIK 12.5 MG TABLET
- SUBOXONE 12 MG-3 MG SL FILM
- LYBALVI 10-10 MG TABLET