BUPROPION HCL SR 100 MG TABLET
For 30 tablets
Pharmacies pay
$2.04 filed
30 × $0.0679 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-09-30 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$6.97 filed
30 × $0.23239 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
3.4× estimated
Medicare paid 3.4× what pharmacies pay.
Part D averages every strength and form sold under “Bupropion HCl SR” / “Bupropion HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23, 2026-09-30 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$7.35 estimated
$2.04 + $0.31 (15%) + $5.00 fee per fill = $7.35
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23, 2026-09-30 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
BUPROPION HCL SR 100 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as bupropion hydrochloride, under the trade name “Bupropion Hydrochloride SR”.
FDA gives its dosage form as “tablet, film coated, extended release” and “tablet, extended release” and its route as oral.
FDA lists 9 labelers (the companies named on the label) for its NDCs, among them Actavis Pharma, Inc., Major Pharmaceuticals and Camber Pharmaceuticals, Inc.
FDA’s Established Pharmacologic Class for it is Aminoketone.
The NADAC file of 2026-10-14 prices it under 21 NDCs (National Drug Codes); the FDA directory lists 20 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $2.04 for 30 tablets (30 × $0.0679 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; those prices took effect between 2026-09-23 and 2026-09-30. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 9 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Camber Pharmaceuticals, Inc. | 3 | $0.0679 per EA filed |
| Dr. Reddy’s Laboratories Inc. | 3 | $0.0679 per EA filed |
| ScieGen Pharmaceuticals, Inc. | 3 | $0.0679 per EA filed |
| Solco Healthcare US LLC | 3 | $0.0679 per EA filed |
| Actavis Pharma, Inc. | 2 | $0.0679 per EA filed |
| Aurobindo Pharma Limited | 2 | $0.0679 per EA filed |
| Epic Pharma, LLC | 2 | $0.0679 per EA filed |
| American Health Packaging | 1 | $0.0679 per EA filed |
| Major Pharmaceuticals | 1 | $0.0679 per EA filed |
| Not listed as a package in the FDA directory | 1 | $0.0679 per EA filed |
When these prices took effect
- 2026-09-30 · 1 NDC · $0.0679 per EA filed
- 2026-09-23 · 20 NDCs · $0.0679 per EA filed
All 21 NDCs, with labeler and price
- 00591-3540-05 · Actavis Pharma, Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 00591-3540-60 · Actavis Pharma, Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 00904-7099-61 · Major Pharmaceuticals · $0.0679 per EA · eff. 2026-09-23 filed
- 31722-0066-01 · Camber Pharmaceuticals, Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 31722-0066-05 · Camber Pharmaceuticals, Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 31722-0066-60 · Camber Pharmaceuticals, Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 42806-0424-01 · Epic Pharma, LLC · $0.0679 per EA · eff. 2026-09-23 filed
- 42806-0424-60 · Epic Pharma, LLC · $0.0679 per EA · eff. 2026-09-23 filed
- 43547-0288-09 · Solco Healthcare US LLC · $0.0679 per EA · eff. 2026-09-23 filed
- 43547-0288-10 · Solco Healthcare US LLC · $0.0679 per EA · eff. 2026-09-23 filed
- 43547-0288-50 · Solco Healthcare US LLC · $0.0679 per EA · eff. 2026-09-23 filed
- 43598-0751-01 · Dr. Reddy’s Laboratories Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 43598-0751-05 · Dr. Reddy’s Laboratories Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 43598-0751-60 · Dr. Reddy’s Laboratories Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 50228-0174-01 · ScieGen Pharmaceuticals, Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 50228-0174-05 · ScieGen Pharmaceuticals, Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 50228-0174-60 · ScieGen Pharmaceuticals, Inc. · $0.0679 per EA · eff. 2026-09-23 filed
- 59651-0846-01 · Aurobindo Pharma Limited · $0.0679 per EA · eff. 2026-09-30 filed
- 59651-0846-05 · Aurobindo Pharma Limited · $0.0679 per EA · eff. 2026-09-23 filed
- 68084-0697-01 · American Health Packaging · $0.0679 per EA · eff. 2026-09-23 filed
- 68084-0697-11 · not listed as a package in the FDA directory · $0.0679 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
10 other products in the NADAC file share the FDA nonproprietary name bupropion hydrochloride with BUPROPION HCL SR 100 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| BUPROPION HCL 75 MG TABLET | $0.09282 per EA filed | $0.28918 per EA filed |
| BUPROPION HCL 100 MG TABLET | $0.11295 per EA filed | $0.28918 per EA filed |
| BUPROPION HCL SR 100 MG TABLET this page | $0.0679 per EA filed | $0.23239 per EA filed |
| BUPROPION HCL SR 150 MG TABLET | $0.07985 to $0.25221 per EA filed | $0.23239 per EA filed |
| BUPROPION HCL SR 200 MG TABLET | $0.10362 per EA filed | $0.23239 per EA filed |
| BUPROPION HCL XL 150 MG TABLET | $0.07846 per EA filed | $0.40383 per EA filed |
| BUPROPION HCL XL 300 MG TABLET | $0.10041 per EA filed | $0.40383 per EA filed |
| BUPROPION HCL XL 450 MG TABLET | $7.99556 per EA filed | $0.40383 per EA filed |
| WELLBUTRIN SR 100 MG TABLET | $7.06228 per EA filed | $8.87963 per EA filed |
| WELLBUTRIN SR 150 MG TABLET | $7.51608 per EA filed | $8.87963 per EA filed |
| WELLBUTRIN SR 200 MG TABLET | $13.97633 per EA filed | $8.87963 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-09-30 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 21 NDCs’ NADAC prices is $0.0679 per EA filed.
Of the 11 other products in FDA’s Aminoketone class priced per EA, 11 have a higher middle NADAC price and 0 a lower one. The one in the middle is BUPROPION HCL 100 MG TABLET, at $0.11295 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $6.97 for 30 tablets, at an average of $0.23239 per EA in 2024 (2024-01-01 to 2024-12-31) for “Bupropion HCl SR” and “Bupropion HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 2,256,886 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for BUPROPION HCL SR 100 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Bupropion HCl SR / Bupropion HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.