CODEINE-GUAIFEN 10-100 MG/5 ML
For 1 mL
Pharmacies pay
$0.03 – $0.06 filed
1 × $0.0327 to $0.06445 per ML (the 4 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$5.03 – $5.07 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
CODEINE-GUAIFEN 10-100 MG/5 ML is how the CMS NADAC file names this product. The FDA NDC Directory lists it as codeine phosphate and guaifenesin, under the trade name “Codeine-Guaifenesin”.
FDA gives its dosage form as solution and its route as oral.
Its labelers, the companies named on the label, are Method Pharmaceuticals, LLC and Westminster Pharmaceuticals, LLC.
FDA lists it under 2 Established Pharmacologic Classes: Expectorant and Opioid Agonist.
The NADAC file of 2026-10-14 prices it under 4 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and marks it as sold over the counter.
What pharmacies pay
Pharmacies pay $0.03 – $0.06 for 1 mL, depending on the NDC ($0.0327 to $0.06445 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
All 4 NDCs
- 58657-0500-04 · Method Pharmaceuticals, LLC · $0.05877 per ML · eff. 2026-09-23 filed
- 58657-0500-16 · Method Pharmaceuticals, LLC · $0.0327 per ML · eff. 2026-09-23 filed
- 69367-0272-04 · Westminster Pharmaceuticals, LLC · $0.06445 per ML · eff. 2026-09-23 filed
- 69367-0272-16 · Westminster Pharmaceuticals, LLC · $0.0327 per ML · eff. 2026-09-23 filed
Compared with its class
The middle of its 4 NDCs’ NADAC prices is $0.0327 per ML filed.
Of the 38 other products in FDA’s Expectorant class priced per ML, 5 have a higher middle NADAC price and 32 a lower one; 1 has the same. The one in the middle is ROBAFEN DM 200-20 MG/20 ML LIQ, at $0.02069 per ML filed (eff. 2026-09-23).
Of the 31 other products in FDA’s Opioid Agonist class priced per ML, 26 have a higher middle NADAC price and 4 a lower one; 1 has the same. The one in the middle is ACETAMINOPHEN-CODEINE 120 MG-12 MG/5 ML SOLUTION, at $0.46877 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $0.0327 to $0.06445 per ML for this product, depending on the NDC.
- It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (118 mL, 120 mL, 473 mL). So the card starts at 1 ML; change it to match your prescription.
Related pages
Its pharmacologic classes
Related in the same class
- GUAIFEN-CODEINE 100-10 MG/5 ML
- TRAMADOL HCL 100 MG TABLET
- OXYCODONE-ACETAMINOPHEN 10-325 MG TAB
- FENTANYL 100 MCG/HR PATCH
- METHADONE HCL 10 MG TABLET