Opioid Agonist
An Established Pharmacologic Class (EPC) in the FDA NDC Directory: the class FDA records for a product in its PHARM_CLASSES field.
In the NADAC file of 2026-10-14
141 products in the NADAC file of 2026-10-14 have an NDC that FDA lists in this class, covering 37 nonproprietary names as FDA writes them. 75 of them have a Medicare figure on OpenBill.
Being in one class means FDA describes the drugs’ pharmacology the same way. It does not mean one can replace another; that is a question for your prescriber.
Prices per unit: CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · as of 2026-10-14 · retrieved 2026-10-17. Classes: FDA NDC Directory · ndctext.zip · as of 2026-10-16.
The products, with what pharmacies pay per unit
- ACETAMINOPHEN-COD #2 TABLET
- ACETAMINOPHEN-COD #3 TABLET
- ACETAMINOPHEN-COD #4 TABLET
- ACETAMINOPHEN-CODEINE 120 MG-12 MG/5 ML SOLUTION
- ANTI-DIARRHEAL 1 MG/7.5 ML SOL
- ANTI-DIARRHEAL 2 MG CAPLET
- ANTI-DIARRHEAL 2 MG SOFTGEL
- ASA-BUTALB-CAFF-COD #3 CAPSULE
- ASCOMP WITH CODEINE CAPSULE
- BUTALBITAL-ACETAMINOPHEN-CAFFEINE-CODEINE 50-300-40-30 MG CP
- BUTALBITAL-ACETAMINOPHEN-CAFFEINE-CODEINE 50-325-40-30 MG CP
- CODEINE SULFATE 15 MG TABLET
- CODEINE SULFATE 30 MG TABLET
- CODEINE SULFATE 60 MG TABLET
- CODEINE-GUAIFEN 10-100 MG/5 ML
- ENDOCET 10-325 MG TABLET
- ENDOCET 2.5-325 MG TABLET
- ENDOCET 5-325 MG TABLET
- ENDOCET 7.5-325 MG TABLET
- FENTANYL 100 MCG/2 ML VIAL
- FENTANYL 100 MCG/HR PATCH
- FENTANYL 12 MCG/HR PATCH
- FENTANYL 2,500 MCG/50 ML VIAL
- FENTANYL 25 MCG/HR PATCH
- FENTANYL 250 MCG/5 ML VIAL
- FENTANYL 37.5 MCG/HR PATCH
- FENTANYL 50 MCG/HR PATCH
- FENTANYL 62.5 MCG/HR PATCH
- FENTANYL 75 MCG/HR PATCH
- FT ANTI-DIARRHEAL 1 MG/7.5 ML
- FT ANTI-DIARRHEAL 2 MG CAPLET
- FT ANTI-DIARRHEAL 2 MG SOFTGEL
- FT ANTI-DIARRHEAL-ANTIGAS CPLT
- GNP ANTI-DIARRHEAL 2 MG TABLET
- GNP ANTI-DIARRHEAL-GAS CPLT
- GS ANTI-DIARRHEAL 1 MG/7.5 ML
- GS ANTI-DIARRHEAL 2 MG CAPLET
- GS ANTI-DIARRHEAL-ANTIGAS CPLT
- GUAIFEN-CODEINE 100-10 MG/5 ML
- HYDROCODONE ER 15 MG CAPSULE
- HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET
- HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET
- HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET
- HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET
- HYDROCODONE-ACETAMINOPHEN 7.5-300 MG TABLET
- HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET
- HYDROCODONE-ACETAMINOPHEN 7.5-325 MG/15 ML SOLUTION
- HYDROCODONE-CHLORPHEN ER SUSP
- HYDROCODONE-HOMATROPINE 5-1.5 MG TABLET
- HYDROCODONE-HOMATROPINE SOLN
- HYDROCODONE-IBUPROFEN 10-200
- HYDROCODONE-IBUPROFEN 5-200 MG
- HYDROCODONE-IBUPROFEN 7.5-200
- HYDROMORPHONE 1 MG/ML SOLUTION
- HYDROMORPHONE 10 MG/ML VIAL
- HYDROMORPHONE 2 MG TABLET
- HYDROMORPHONE 2 MG/ML VIAL
- HYDROMORPHONE 4 MG TABLET
- HYDROMORPHONE 5 MG/5 ML SOLN
- HYDROMORPHONE 50 MG/5 ML VIAL
- HYDROMORPHONE 500 MG/50 ML VIAL
- HYDROMORPHONE 500 MG/50 ML VL
- HYDROMORPHONE 8 MG TABLET
- HYDROMORPHONE HCL ER 12 MG TAB
- HYDROMORPHONE HCL ER 16 MG TAB
- HYDROMORPHONE HCL ER 8 MG TAB
- HYSINGLA ER 20 MG TABLET
- HYSINGLA ER 30 MG TABLET
- HYSINGLA ER 40 MG TABLET
- HYSINGLA ER 60 MG TABLET
- HYSINGLA ER 80 MG TABLET
- LEVORPHANOL 2 MG TABLET
- LOPERAMIDE 1 MG/7.5 ML SOLN
- LOPERAMIDE 2 MG CAPSULE
- LOPERAMIDE-SIMETH 2-125 MG TAB
- MEPERIDINE 50 MG/5 ML SOLUTION
- METHADONE 10 MG/ML ORAL CONC
- METHADONE HCL 10 MG TABLET
- METHADONE HCL 5 MG TABLET
- METHADONE INTENSOL 10 MG/ML
- MORPHINE SULF 10 MG/5 ML SOLN
- MORPHINE SULF 100 MG/5 ML CONC
- MORPHINE SULF 20 MG/5 ML SOLN
- MORPHINE SULF ER 100 MG TABLET
- MORPHINE SULF ER 15 MG TABLET
- MORPHINE SULF ER 200 MG TABLET
- MORPHINE SULF ER 30 MG TABLET
- MORPHINE SULF ER 60 MG TABLET
- MORPHINE SULFATE 10 MG/ML VIAL
- MORPHINE SULFATE 4 MG/ML VIAL
- MORPHINE SULFATE ER 10 MG CAP
- MORPHINE SULFATE ER 20 MG CAP
- MORPHINE SULFATE IR 15 MG TAB
- MORPHINE SULFATE IR 30 MG TAB
- MS CONTIN ER 15 MG TABLET
- MS CONTIN ER 30 MG TABLET
- OPIUM TINCTURE 10 MG/ML
- OXYCODONE HCL (IR) 10 MG TAB
- OXYCODONE HCL (IR) 15 MG TAB
- OXYCODONE HCL (IR) 20 MG TAB
- OXYCODONE HCL (IR) 30 MG TAB
- OXYCODONE HCL (IR) 5 MG CAP
- OXYCODONE HCL (IR) 5 MG TABLET
- OXYCODONE HCL 100 MG/5 ML CONC
- OXYCODONE HCL 5 MG/5 ML SOLN
- OXYCODONE-ACETAMINOPHEN 10-325 MG TAB
- OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET
- OXYCODONE-ACETAMINOPHEN 2.5-325 MG TABLET
- OXYCODONE-ACETAMINOPHEN 5-325 MG TAB
- OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET
- OXYCODONE-ACETAMINOPHEN 7.5-325 MG TABLET
- OXYCONTIN ER 10 MG TABLET
- OXYCONTIN ER 15 MG TABLET
- OXYCONTIN ER 20 MG TABLET
- OXYCONTIN ER 30 MG TABLET
- OXYCONTIN ER 40 MG TABLET
- OXYCONTIN ER 60 MG TABLET
- OXYCONTIN ER 80 MG TABLET
- PERCOCET 10-325 MG TABLET
- PERCOCET 5-325 MG TABLET
- PERCOCET 7.5-325 MG TABLET
- PROMETHAZINE-CODEINE SOLUTION
- QC ANTI-DIARRHEAL 2 MG CAPLET
- QC ANTI-DIARRHEAL 2 MG SOFTGEL
- ROXICODONE 15 MG TABLET
- ROXICODONE 30 MG TABLET
- TAPENTADOL ER 100 MG TABLET
- TAPENTADOL ER 200 MG TABLET
- TAPENTADOL ER 50 MG TABLET
- TAPENTADOL HCL 100 MG TABLET
- TAPENTADOL HCL 50 MG TABLET
- TAPENTADOL HCL 75 MG TABLET
- TRAMADOL HCL 100 MG TABLET
- TRAMADOL HCL 25 MG TABLET
- TRAMADOL HCL 50 MG TABLET
- TRAMADOL HCL ER 100 MG CAPSULE
- TRAMADOL HCL ER 100 MG TABLET
- TRAMADOL HCL ER 200 MG CAPSULE
- TRAMADOL HCL ER 200 MG TABLET
- TRAMADOL HCL ER 300 MG TABLET
- TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB
How to read these prices
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- A price is a range to expect, never a quote.
- Medicare's price is not your price. Say so on every screen that shows it.
- State which dataset and which effective date produced every figure.
- If a source is stale or a file is empty, show that rather than a zero.
- Disclaimer footer: not medical advice, no warranty, other people's data can be wrong.