COSOPT EYE DROPS

What it is

COSOPT EYE DROPS is how the CMS NADAC file names this product. The FDA NDC Directory lists it as dorzolamide hydrochloride and timolol maleate, under the trade name “COSOPT”.

FDA gives its dosage form as solution/ drops and its route as ophthalmic.

The labeler, the company named on the label, is Thea Pharma Inc.

FDA lists it under 2 Established Pharmacologic Classes: beta-Adrenergic Blocker and Carbonic Anhydrase Inhibitor.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 82584-0605-10.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $231.62 for 10 mL (10 × $23.16154 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $0.89267 per ML filed.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What NADAC measures · NADAC explanation codes

The NDC

• 82584-0605-10 · Thea Pharma Inc. · $23.16154 per ML · eff. 2026-09-23 filed

Other strengths, forms and brands

3 other products in the NADAC file share the FDA nonproprietary name dorzolamide hydrochloride and timolol maleate with COSOPT EYE DROPS.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

Its NADAC price is $23.16154 per ML filed.

Of the 19 other products in FDA’s beta-Adrenergic Blocker class priced per ML, 4 have a higher middle NADAC price and 15 a lower one. The one in the middle is TIMOLOL 0.25% GEL-SOLUTION, at $6.37609 per ML filed (eff. 2026-09-23).

Of the 5 other products in FDA’s Carbonic Anhydrase Inhibitor class priced per ML, 2 have a higher middle NADAC price and 3 a lower one. The one in the middle is BRINZOLAMIDE 1% EYE DROPS, at $8.52641 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $223.75 for 10 mL, at an average of $22.37467 per ML in 2024 (2024-01-01 to 2024-12-31) for “Cosopt” and “Dorzolamide HCl/Timolol Maleat”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 1,932 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 10 mL? Is it lower than what I would pay through my insurance?
• Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: DORZOLAMIDE-TIMOLOL 2-0.5%(PF). Ask your pharmacist or prescriber; do not switch on your own.
• How much is in the package I am getting? This page uses 10 mL; your package may hold a different amount.
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.