BRINZOLAMIDE 1% EYE DROPS
For 1 mL
Pharmacies pay
$8.53 – $9.47 filed
1 × $8.52641 to $9.474 per ML (the 8 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$14.61 filed
1 × $14.60786 per ML, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.5× – 1.7× estimated
Medicare paid between 1.5× and 1.7× what pharmacies pay, depending on the NDC.
Part D averages every strength and form sold under “Brinzolamide” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$14.81 – $15.89 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
BRINZOLAMIDE 1% EYE DROPS is how the CMS NADAC file names this product. The FDA NDC Directory lists it as brinzolamide.
FDA gives its dosage form as suspension/ drops and its route as ophthalmic.
Its labelers, the companies named on the label, are Padagis US LLC, Sandoz Inc and Bausch & Lomb Incorporated.
FDA’s Established Pharmacologic Class for it is Carbonic Anhydrase Inhibitor.
The NADAC file of 2026-10-14 prices it under 8 NDCs (National Drug Codes); the FDA directory lists 6 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $8.53 – $9.47 for 1 mL, depending on the NDC ($8.52641 to $9.474 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · NADAC explanation codes
The 3 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Bausch & Lomb Incorporated | 2 | $8.52641 to $9.474 per ML filed |
| Padagis US LLC | 2 | $8.52641 to $9.474 per ML filed |
| Sandoz Inc | 2 | $8.52641 to $9.474 per ML filed |
| Not listed as a package in the FDA directory | 2 | $8.52641 to $9.474 per ML filed |
All 8 NDCs, with labeler and price
- 00574-4012-10 · Padagis US LLC · $8.52641 per ML · eff. 2026-09-23 filed
- 00574-4012-15 · Padagis US LLC · $9.474 per ML · eff. 2026-09-23 filed
- 00591-2127-12 · not listed as a package in the FDA directory · $9.474 per ML · eff. 2026-09-23 filed
- 00591-2127-79 · not listed as a package in the FDA directory · $8.52641 per ML · eff. 2026-09-23 filed
- 00781-6014-70 · Sandoz Inc · $8.52641 per ML · eff. 2026-09-23 filed
- 00781-6014-85 · Sandoz Inc · $9.474 per ML · eff. 2026-09-23 filed
- 24208-0464-10 · Bausch & Lomb Incorporated · $8.52641 per ML · eff. 2026-09-23 filed
- 24208-0464-15 · Bausch & Lomb Incorporated · $9.474 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
1 other product in the NADAC file shares the FDA nonproprietary name brinzolamide with BRINZOLAMIDE 1% EYE DROPS.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| AZOPT 1% EYE DROPS | $35.06272 to $35.29803 per ML filed | $35.40014 per ML filed |
| BRINZOLAMIDE 1% EYE DROPS this page | $8.52641 to $9.474 per ML filed | $14.60786 per ML filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 8 NDCs’ NADAC prices is $8.52641 per ML filed.
Of the 5 other products in FDA’s Carbonic Anhydrase Inhibitor class priced per ML, 3 have a higher middle NADAC price and 2 a lower one. The one in the middle is COSOPT EYE DROPS, at $23.16154 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $14.61 for 1 mL, at an average of $14.60786 per ML in 2024 (2024-01-01 to 2024-12-31) for “Brinzolamide”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 193,228 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $8.52641 to $9.474 per ML for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for BRINZOLAMIDE 1% EYE DROPS labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Brinzolamide / Brinzolamide: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on generic name.
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (10 mL, 15 mL). So the card starts at 1 ML; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- DORZOLAMIDE-TIMOLOL EYE DROPS
- DORZOLAMIDE HCL 2% EYE DROPS
- SIMBRINZA 1%-0.2% EYE DROP
- ACETAZOLAMIDE 125 MG TABLET