CRINONE 4% GEL
FDA nonproprietary name: progesterone
For 6.75 g
Pharmacies pay
$113.70 filed
6.75 × $16.84389 per GM
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-02 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$137.07 filed
6.75 × $20.30736 per GM, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.2× estimated
Medicare paid 1.2× what pharmacies pay.
Part D averages every strength and form sold under “Crinone” / “Progesterone, Micronized” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-01-02 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$135.76 estimated
$113.70 + $17.06 (15%) + $5.00 fee per fill = $135.76
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-01-02 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
CRINONE 4% GEL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as progesterone, under the trade name “Crinone”.
FDA gives its dosage form as gel and its route as vaginal.
The labeler, the company named on the label, is Allergan, Inc.
FDA’s Established Pharmacologic Class for it is Progesterone.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00023-6150-04.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $113.70 for 6.75 g (6.75 × $16.84389 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-01-02. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size.
This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-01-02. The file is new; the price is not.
What NADAC measures · NADAC explanation codes · Carried-forward prices
The NDC
- 00023-6150-04 · Allergan, Inc. · $16.84389 per GM · eff. 2026-01-02 filed carried forward
Other strengths, forms and brands
8 other products in the NADAC file share the FDA nonproprietary name progesterone with CRINONE 4% GEL.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CRINONE 4% GEL this page | $16.84389 per GM filed | $20.30736 per GM filed |
| CRINONE 8% GEL | $27.97261 per GM filed | $20.30736 per GM filed |
| ENDOMETRIN 100 MG VAG INSERT | $15.15184 per EA filed | We don’t know yet |
| PROGESTERONE 100 MG CAPSULE | $0.22903 per EA filed | We don’t know yet |
| PROGESTERONE 100 MG VAG INSERT | $10.87559 per EA filed | We don’t know yet |
| PROGESTERONE 200 MG CAPSULE | $0.40405 per EA filed | We don’t know yet |
| PROGESTERONE 500 MG/10 ML VIAL | $1.36055 per ML filed | $0.623 per ML derived |
| PROMETRIUM 100 MG CAPSULE | $15.90949 per EA filed | $17.69378 per EA filed |
| PROMETRIUM 200 MG CAPSULE | $30.39475 per EA filed | $17.69378 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-02, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
What Medicare paid
Medicare Part D paid $137.07 for 6.75 g, at an average of $20.30736 per GM in 2024 (2024-01-01 to 2024-12-31) for “Crinone” and “Progesterone, Micronized”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 124 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 6.75 g? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 6.75 g; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for CRINONE 4% GEL labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Crinone / Progesterone, Micronized: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on brand name.
- Why does this page start at 6.75 g?
- NADAC prices this product per GM. The FDA NDC Directory’s package description gives 6.75 g in one package for this product’s NDC (“6 APPLICATOR in 1 CARTON (0023-6150-04) / 1.125 g in 1 APPLICATOR”), so the card starts at one package: 6.75 GM. Change it to match your prescription.