PROGESTERONE 500 MG/10 ML VIAL
For 1 mL
Pharmacies pay
$1.36 filed
1 × $1.36055 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$0.62 derived
1 × $0.623 per ML, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
0.46× estimated
Medicare pays 54% less than pharmacies pay.
5 labelers share HCPCS J2675 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$6.56 estimated
$1.36 + $0.20 (15%) + $5.00 fee per fill = $6.56
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
PROGESTERONE 500 MG/10 ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as progesterone.
FDA gives its dosage form as “injection” and “injection, solution” and its route as intramuscular.
FDA lists 4 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., Eugia US LLC and Fresenius Kabi USA, LLC.
FDA’s Established Pharmacologic Class for it is Progesterone.
The NADAC file of 2026-10-14 prices it under 5 NDCs (National Drug Codes); the FDA directory lists 4 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.36 for 1 mL (1 × $1.36055 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
All 5 NDCs
- 00143-9725-01 · Hikma Pharmaceuticals USA Inc. · $1.36055 per ML · eff. 2026-09-23 filed
- 00591-3128-79 · not listed as a package in the FDA directory · $1.36055 per ML · eff. 2026-09-23 filed
- 55150-0306-10 · Eugia US LLC · $1.36055 per ML · eff. 2026-09-23 filed
- 63323-0261-10 · Fresenius Kabi USA, LLC · $1.36055 per ML · eff. 2026-09-23 filed
- 70700-0286-22 · XIROMED, LLC · $1.36055 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
8 other products in the NADAC file share the FDA nonproprietary name progesterone with PROGESTERONE 500 MG/10 ML VIAL.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CRINONE 4% GEL | $16.84389 per GM filed | $20.30736 per GM filed |
| CRINONE 8% GEL | $27.97261 per GM filed | $20.30736 per GM filed |
| ENDOMETRIN 100 MG VAG INSERT | $15.15184 per EA filed | We don’t know yet |
| PROGESTERONE 100 MG CAPSULE | $0.22903 per EA filed | We don’t know yet |
| PROGESTERONE 100 MG VAG INSERT | $10.87559 per EA filed | We don’t know yet |
| PROGESTERONE 200 MG CAPSULE | $0.40405 per EA filed | We don’t know yet |
| PROGESTERONE 500 MG/10 ML VIAL this page | $1.36055 per ML filed | $0.623 per ML derived |
| PROMETRIUM 100 MG CAPSULE | $15.90949 per EA filed | $17.69378 per EA filed |
| PROMETRIUM 200 MG CAPSULE | $30.39475 per EA filed | $17.69378 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-02, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
What Medicare paid
Medicare Part B’s payment limit for HCPCS J2675, for 2026-10-01 to 2026-12-31, comes to $0.62 for 1 mL, or $0.623 per ML once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.1246 per 50 MG.
3 of the product’s 5 NDCs have this Medicare figure; the other 2 do not, and the interactive card says why for each.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 mL?
- The FDA package description of NDC 00143-9725-01 (“10 INJECTION in 1 BOX (0143-9725-01)”) does not give one amount in mL, NADAC’s unit for this product. So the card starts at 1 ML; change it to match your prescription.