DONEPEZIL HCL 5 MG TABLET
For 30 tablets
Pharmacies pay
$1.32 filed
30 × $0.04395 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$7.40 filed
30 × $0.2467 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
5.6× estimated
Medicare paid 5.6× what pharmacies pay.
Part D averages every strength and form sold under “Donepezil HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$6.52 estimated
$1.32 + $0.20 (15%) + $5.00 fee per fill = $6.52
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DONEPEZIL HCL 5 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as donepezil hydrochloride, under the trade name “Donepezil”.
FDA gives its dosage form as “tablet, film coated” and “tablet” and its route as oral.
FDA lists 9 labelers (the companies named on the label) for its NDCs, among them Major Pharmaceuticals, Torrent Pharmaceuticals Limited and Rising Pharma Holdings, Inc.
FDA’s Established Pharmacologic Class for it is Cholinesterase Inhibitor.
The NADAC file of 2026-10-14 prices it under 27 NDCs (National Drug Codes); the FDA directory lists 22 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.32 for 30 tablets (30 × $0.04395 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 9 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Rising Pharma Holdings, Inc. | 4 | $0.04395 per EA filed |
| Alembic Pharmaceuticals Inc. | 3 | $0.04395 per EA filed |
| Camber Pharmaceuticals, Inc. | 3 | $0.04395 per EA filed |
| Macleods Pharmaceuticals Limited | 3 | $0.04395 per EA filed |
| Solco Healthcare US, LLC | 3 | $0.04395 per EA filed |
| Torrent Pharmaceuticals Limited | 3 | $0.04395 per EA filed |
| American Health Packaging | 1 | $0.04395 per EA filed |
| Major Pharmaceuticals | 1 | $0.04395 per EA filed |
| Quallent Pharmaceuticals Health LLC | 1 | $0.04395 per EA filed |
| Not listed as a package in the FDA directory | 5 | $0.04395 per EA filed |
All 27 NDCs, with labeler and price
- 00904-6477-61 · Major Pharmaceuticals · $0.04395 per EA · eff. 2026-09-23 filed
- 13668-0102-10 · Torrent Pharmaceuticals Limited · $0.04395 per EA · eff. 2026-09-23 filed
- 13668-0102-30 · Torrent Pharmaceuticals Limited · $0.04395 per EA · eff. 2026-09-23 filed
- 13668-0102-90 · Torrent Pharmaceuticals Limited · $0.04395 per EA · eff. 2026-09-23 filed
- 16571-0778-03 · Rising Pharma Holdings, Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 16571-0778-09 · Rising Pharma Holdings, Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 16571-0778-10 · Rising Pharma Holdings, Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 16571-0778-50 · Rising Pharma Holdings, Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 31722-0737-05 · Camber Pharmaceuticals, Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 31722-0737-30 · Camber Pharmaceuticals, Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 31722-0737-90 · Camber Pharmaceuticals, Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 33342-0027-07 · Macleods Pharmaceuticals Limited · $0.04395 per EA · eff. 2026-09-23 filed
- 33342-0027-10 · Macleods Pharmaceuticals Limited · $0.04395 per EA · eff. 2026-09-23 filed
- 33342-0027-15 · Macleods Pharmaceuticals Limited · $0.04395 per EA · eff. 2026-09-23 filed
- 43547-0275-03 · Solco Healthcare US, LLC · $0.04395 per EA · eff. 2026-09-23 filed
- 43547-0275-09 · Solco Healthcare US, LLC · $0.04395 per EA · eff. 2026-09-23 filed
- 43547-0275-11 · Solco Healthcare US, LLC · $0.04395 per EA · eff. 2026-09-23 filed
- 60687-0292-01 · American Health Packaging · $0.04395 per EA · eff. 2026-09-23 filed
- 60687-0292-11 · not listed as a package in the FDA directory · $0.04395 per EA · eff. 2026-09-23 filed
- 62332-0092-30 · Alembic Pharmaceuticals Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 62332-0092-90 · Alembic Pharmaceuticals Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 62332-0092-91 · Alembic Pharmaceuticals Inc. · $0.04395 per EA · eff. 2026-09-23 filed
- 71093-0127-01 · not listed as a package in the FDA directory · $0.04395 per EA · eff. 2026-09-23 filed
- 71093-0127-03 · not listed as a package in the FDA directory · $0.04395 per EA · eff. 2026-09-23 filed
- 71093-0127-05 · not listed as a package in the FDA directory · $0.04395 per EA · eff. 2026-09-23 filed
- 71093-0127-06 · not listed as a package in the FDA directory · $0.04395 per EA · eff. 2026-09-23 filed
- 82009-0119-05 · Quallent Pharmaceuticals Health LLC · $0.04395 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
4 other products in the NADAC file share the FDA nonproprietary name donepezil hydrochloride with DONEPEZIL HCL 5 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| DONEPEZIL HCL 5 MG TABLET this page | $0.04395 per EA filed | $0.2467 per EA filed |
| DONEPEZIL HCL 10 MG TABLET | $0.04843 per EA filed | $0.2467 per EA filed |
| DONEPEZIL HCL 23 MG TABLET | $0.73542 per EA filed | $0.2467 per EA filed |
| DONEPEZIL HCL ODT 5 MG TABLET | $0.28066 per EA filed | $0.54521 per EA filed |
| DONEPEZIL HCL ODT 10 MG TABLET | $0.29119 per EA filed | $0.54521 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 27 NDCs’ NADAC prices is $0.04395 per EA filed.
Of the 28 other products in FDA’s Cholinesterase Inhibitor class priced per EA, 28 have a higher middle NADAC price and 0 a lower one. The one in the middle is GALANTAMINE ER 16 MG CAPSULE, at $0.846 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $7.40 for 30 tablets, at an average of $0.2467 per EA in 2024 (2024-01-01 to 2024-12-31) for “Donepezil HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 8,063,081 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for DONEPEZIL HCL 5 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Donepezil HCl / Donepezil HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
Related pages
Its pharmacologic class
Related in the same class
- NAMZARIC 14 MG-10 MG CAPSULE
- PYRIDOSTIGMINE ER 180 MG TAB
- EXELON 4.6 MG/24HR PATCH
- MALATHION 0.5% LOTION
- GALANTAMINE HBR 12 MG TABLET