PYRIDOSTIGMINE ER 180 MG TAB
For 30 tablets
Pharmacies pay
$119.89 filed
30 × $3.99632 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$200.84 filed
30 × $6.69477 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.7× estimated
Medicare paid 1.7× what pharmacies pay.
Part D averages every strength and form sold under “Pyridostigmine Bromide ER” / “Pyridostigmine Bromide” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$142.87 estimated
$119.89 + $17.98 (15%) + $5.00 fee per fill = $142.87
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
PYRIDOSTIGMINE ER 180 MG TAB is how the CMS NADAC file names this product. The FDA NDC Directory lists it as pyridostigmine bromide.
FDA gives its dosage form as “tablet, extended release” and “tablet” and its route as oral.
Its labelers, the companies named on the label, are Alvogen, Inc. and Rising Pharma Holdings, Inc.
FDA’s Established Pharmacologic Class for it is Cholinesterase Inhibitor.
The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes); the FDA directory lists 2 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $119.89 for 30 tablets (30 × $3.99632 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
All 3 NDCs
- 00115-1404-08 · not listed as a package in the FDA directory · $3.99632 per EA · eff. 2026-09-23 filed
- 47781-0335-30 · Alvogen, Inc. · $3.99632 per EA · eff. 2026-09-23 filed
- 64980-0220-03 · Rising Pharma Holdings, Inc. · $3.99632 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
3 other products in the NADAC file share the FDA nonproprietary name pyridostigmine bromide with PYRIDOSTIGMINE ER 180 MG TAB.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| PYRIDOSTIGMINE 60 MG/5 ML SOLN | $0.56484 per ML filed | We don’t know yet |
| PYRIDOSTIGMINE BR 30 MG TABLET | $6.94704 per EA filed | We don’t know yet |
| PYRIDOSTIGMINE BR 60 MG TABLET | $0.24872 per EA filed | We don’t know yet |
| PYRIDOSTIGMINE ER 180 MG TAB this page | $3.99632 per EA filed | $6.69477 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 3 NDCs’ NADAC prices is $3.99632 per EA filed.
Of the 28 other products in FDA’s Cholinesterase Inhibitor class priced per EA, 9 have a higher middle NADAC price and 19 a lower one. The one in the middle is GALANTAMINE ER 8 MG CAPSULE, at $0.80235 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $200.84 for 30 tablets, at an average of $6.69477 per EA in 2024 (2024-01-01 to 2024-12-31) for “Pyridostigmine Bromide ER” and “Pyridostigmine Bromide”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 16,981 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for PYRIDOSTIGMINE ER 180 MG TAB labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Pyridostigmine Bromide ER / Pyridostigmine Bromide: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
Related pages
Its pharmacologic class
Related in the same class
- DONEPEZIL HCL 10 MG TABLET
- GALANTAMINE ER 16 MG CAPSULE
- NAMZARIC 14 MG-10 MG CAPSULE
- EXELON 4.6 MG/24HR PATCH
- MALATHION 0.5% LOTION