DOXYCYCLINE 50 MG TABLET
For 30 tablets
Pharmacies pay
$140.99 filed
30 × $4.69979 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$14.56 filed
30 × $0.48521 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.10× estimated
These two figures may not measure the same thing
At 0.10×, the Medicare figure is 0.2 times what pharmacies pay or less. A gap that large means the two figures may not describe the same unit or product, or the price may have changed between their dates; check what each one covers before relying on the multiple.
This product’s middle NADAC price, $4.69979 per EA, is 39.8× the middle NADAC price of the 6 other products CMS averages under “Doxycycline Hyclate*” / “Doxycycline Hyclate” ($0.11799 per EA), so the Part D average may mostly describe those products, not this one.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$167.14 estimated
$140.99 + $21.15 (15%) + $5.00 fee per fill = $167.14
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DOXYCYCLINE 50 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as doxycycline hyclate.
FDA gives its dosage form as “tablet, film coated” and “tablet” and its route as oral.
Its labelers, the companies named on the label, are Chartwell RX LLC, Alembic Pharmaceuticals Inc. and Strides Pharma Science Limited.
FDA’s Established Pharmacologic Class for it is Tetracycline-class Drug.
The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $140.99 for 30 tablets (30 × $4.69979 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
All 3 NDCs
- 62135-0625-60 · Chartwell RX LLC · $4.69979 per EA · eff. 2026-09-23 filed
- 62332-0499-60 · Alembic Pharmaceuticals Inc. · $4.69979 per EA · eff. 2026-09-23 filed
- 64380-0225-01 · Strides Pharma Science Limited · $4.69979 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
10 other products in the NADAC file share the FDA nonproprietary name doxycycline hyclate with DOXYCYCLINE 50 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| DORYX MPC DR 60 MG TABLET | $18.1822 per EA filed | We don’t know yet |
| DOXYCYCLINE 50 MG TABLET this page | $4.69979 per EA filed | $0.48521 per EA filed |
| DOXYCYCLINE HYC DR 50 MG TAB | $1.56942 per EA filed | We don’t know yet |
| DOXYCYCLINE HYC DR 100 MG TAB | $2.18358 per EA filed | We don’t know yet |
| DOXYCYCLINE HYC DR 200 MG TAB | $5.17223 per EA filed | We don’t know yet |
| DOXYCYCLINE HYCLATE 20 MG TAB | $0.09837 per EA filed | $0.48521 per EA filed |
| DOXYCYCLINE HYCLATE 50 MG CAP | $0.14441 per EA filed | $0.48521 per EA filed |
| DOXYCYCLINE HYCLATE 75 MG TAB | $0.54817 per EA filed | $0.48521 per EA filed |
| DOXYCYCLINE HYCLATE 100 MG CAP | $0.1049 per EA filed | $0.48521 per EA filed |
| DOXYCYCLINE HYCLATE 100 MG TAB | $0.11799 per EA filed | $0.48521 per EA filed |
| DOXYCYCLINE HYCLATE 150 MG TAB | $0.72427 per EA filed | $0.48521 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-12-17, 2026-04-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 3 NDCs’ NADAC prices is $4.69979 per EA filed.
Of the 25 other products in FDA’s Tetracycline-class Drug class priced per EA, 3 have a higher middle NADAC price and 22 a lower one. The one in the middle is MINOCYCLINE HCL 50 MG TABLET, at $0.34351 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $14.56 for 30 tablets, at an average of $0.48521 per EA in 2024 (2024-01-01 to 2024-12-31) for “Doxycycline Hyclate*” and “Doxycycline Hyclate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 6,667,052 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for DOXYCYCLINE 50 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: Part D averages every strength and form sold under “Doxycycline Hyclate*” / “Doxycycline Hyclate” into one figure, so it is not specific to this NDC. The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Doxycycline Hyclate* / Doxycycline Hyclate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes ORAL point at this name (76 of the 83 the name join matched); NDCs of another route or with no known FDA route do not. 5 of the 76 NDCs that point at this name are not listed in the FDA NDC Directory as packages of their own; their route was taken from FDA's record for the same product (labeler and product code).