OpenBilldrug price receipt

NADAC week of 2026-10-14

DOXYCYCLINE HYCLATE 100 MG TAB

For 30 tablets

Pharmacies pay

$3.54 filed

30 × $0.11799 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$14.56 filed

30 × $0.48521 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

4.1× estimated

Medicare paid 4.1× what pharmacies pay.

Part D averages every strength and form sold under “Doxycycline Hyclate*” / “Doxycycline Hyclate” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$9.07 estimated

$3.54 + $0.53 (15%) + $5.00 fee per fill = $9.07

This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

DOXYCYCLINE HYCLATE 100 MG TAB is how the CMS NADAC file names this product. The FDA NDC Directory lists it as doxycycline hyclate, under the trade name “Doxycycline”.

FDA gives its dosage form as “tablet, coated”, “tablet” and “tablet, film coated” and its route as oral.

FDA lists 12 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., Actavis Pharma, Inc. and Major Pharmaceuticals.

FDA’s Established Pharmacologic Class for it is Tetracycline-class Drug.

The NADAC file of 2026-10-14 prices it under 40 NDCs (National Drug Codes); the FDA directory lists 32 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $3.54 for 30 tablets (30 × $0.11799 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

The 12 labelers

LabelerNDCsPharmacies pay per unit
PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS9$0.11799 per EA filed
Chartwell RX LLC5$0.11799 per EA filed
Major Pharmaceuticals3$0.11799 per EA filed
Actavis Pharma, Inc.2$0.11799 per EA filed
Cranbury Pharmaceuticals, LLC2$0.11799 per EA filed
Epic Pharma, LLC2$0.11799 per EA filed
Hikma Pharmaceuticals USA Inc.2$0.11799 per EA filed
Sun Pharmaceutical Industries, Inc.2$0.11799 per EA filed
Viona Pharmaceuticals Inc2$0.11799 per EA filed
Acella Pharmaceuticals, LLC1$0.11799 per EA filed
American Health Packaging1$0.11799 per EA filed
AvPAK1$0.11799 per EA filed
Not listed as a package in the FDA directory8$0.11799 per EA filed
All 40 NDCs, with labeler and price
  • 00143-2112-05 · Hikma Pharmaceuticals USA Inc. · $0.11799 per EA · eff. 2026-09-23 filed
  • 00143-2112-50 · Hikma Pharmaceuticals USA Inc. · $0.11799 per EA · eff. 2026-09-23 filed
  • 00591-5553-05 · Actavis Pharma, Inc. · $0.11799 per EA · eff. 2026-09-23 filed
  • 00591-5553-50 · Actavis Pharma, Inc. · $0.11799 per EA · eff. 2026-09-23 filed
  • 00904-0430-04 · Major Pharmaceuticals · $0.11799 per EA · eff. 2026-09-23 filed
  • 00904-0430-06 · Major Pharmaceuticals · $0.11799 per EA · eff. 2026-09-23 filed
  • 00904-0430-95 · Major Pharmaceuticals · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0310-01 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0310-05 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0310-07 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0310-08 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0310-10 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0310-20 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0310-21 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0310-30 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0310-50 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0312-01 · not listed as a package in the FDA directory · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0312-05 · not listed as a package in the FDA directory · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0312-10 · not listed as a package in the FDA directory · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0312-20 · not listed as a package in the FDA directory · $0.11799 per EA · eff. 2026-09-23 filed
  • 24658-0312-50 · not listed as a package in the FDA directory · $0.11799 per EA · eff. 2026-09-23 filed
  • 27808-0234-01 · Cranbury Pharmaceuticals, LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 27808-0234-02 · Cranbury Pharmaceuticals, LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 42192-0501-05 · Acella Pharmaceuticals, LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 42806-0310-05 · Epic Pharma, LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 42806-0310-50 · Epic Pharma, LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 50268-0279-11 · not listed as a package in the FDA directory · $0.11799 per EA · eff. 2026-09-23 filed
  • 50268-0279-15 · AvPAK · $0.11799 per EA · eff. 2026-09-23 filed
  • 53489-0120-02 · Sun Pharmaceutical Industries, Inc. · $0.11799 per EA · eff. 2026-09-23 filed
  • 53489-0120-05 · Sun Pharmaceutical Industries, Inc. · $0.11799 per EA · eff. 2026-09-23 filed
  • 62135-0626-01 · Chartwell RX LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 62135-0626-05 · Chartwell RX LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 62135-0626-10 · Chartwell RX LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 62135-0626-50 · Chartwell RX LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 62135-0626-96 · Chartwell RX LLC · $0.11799 per EA · eff. 2026-09-23 filed
  • 62584-0693-11 · not listed as a package in the FDA directory · $0.11799 per EA · eff. 2026-09-23 filed
  • 62584-0693-21 · American Health Packaging · $0.11799 per EA · eff. 2026-09-23 filed
  • 72578-0001-05 · Viona Pharmaceuticals Inc · $0.11799 per EA · eff. 2026-09-23 filed
  • 72578-0001-18 · Viona Pharmaceuticals Inc · $0.11799 per EA · eff. 2026-09-23 filed
  • 85477-0501-05 · not listed as a package in the FDA directory · $0.11799 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

10 other products in the NADAC file share the FDA nonproprietary name doxycycline hyclate with DOXYCYCLINE HYCLATE 100 MG TAB.

ProductPharmacies pay per unitMedicare per unit
DORYX MPC DR 60 MG TABLET
brand · tablet, delayed release
$18.1822 per EA filed
eff. 2025-12-17
We don’t know yet
DOXYCYCLINE 50 MG TABLET
generic · tablet, film coated / tablet
$4.69979 per EA filed
eff. 2026-09-23
$0.48521 per EA filed
Part D 2024 average
DOXYCYCLINE HYC DR 50 MG TAB
generic · tablet, delayed release
$1.56942 per EA filed
eff. 2026-04-22
We don’t know yet
DOXYCYCLINE HYC DR 100 MG TAB
generic · tablet, delayed release
$2.18358 per EA filed
eff. 2026-09-23
We don’t know yet
DOXYCYCLINE HYC DR 200 MG TAB
generic · tablet, delayed release
$5.17223 per EA filed
eff. 2026-09-23
We don’t know yet
DOXYCYCLINE HYCLATE 20 MG TAB
generic · tablet / tablet, film coated
$0.09837 per EA filed
eff. 2026-09-23
$0.48521 per EA filed
Part D 2024 average
DOXYCYCLINE HYCLATE 50 MG CAP
generic · capsule
$0.14441 per EA filed
eff. 2026-09-23
$0.48521 per EA filed
Part D 2024 average
DOXYCYCLINE HYCLATE 75 MG TAB
generic · tablet / tablet, film coated / tablet, coated
$0.54817 per EA filed
eff. 2026-09-23
$0.48521 per EA filed
Part D 2024 average
DOXYCYCLINE HYCLATE 100 MG CAP
generic · capsule
$0.1049 per EA filed
eff. 2026-09-23
$0.48521 per EA filed
Part D 2024 average
DOXYCYCLINE HYCLATE 100 MG TAB this page
generic · tablet, coated / tablet / tablet, film coated
$0.11799 per EA filed
eff. 2026-09-23
$0.48521 per EA filed
Part D 2024 average
DOXYCYCLINE HYCLATE 150 MG TAB
generic · tablet / tablet, film coated / tablet, coated
$0.72427 per EA filed
eff. 2026-09-23
$0.48521 per EA filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-12-17, 2026-04-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 40 NDCs’ NADAC prices is $0.11799 per EA filed.

Of the 25 other products in FDA’s Tetracycline-class Drug class priced per EA, 23 have a higher middle NADAC price and 2 a lower one. The one in the middle is MINOCYCLINE 75 MG CAPSULE, at $0.39676 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $14.56 for 30 tablets, at an average of $0.48521 per EA in 2024 (2024-01-01 to 2024-12-31) for “Doxycycline Hyclate*” and “Doxycycline Hyclate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 6,667,052 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

34 of the product’s 40 NDCs have this Medicare figure; the other 6 do not, and the interactive card says why for each.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for DOXYCYCLINE HYCLATE 100 MG TAB labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Doxycycline Hyclate* / Doxycycline Hyclate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes ORAL point at this name (76 of the 83 the name join matched); NDCs of another route or with no known FDA route do not. 5 of the 76 NDCs that point at this name are not listed in the FDA NDC Directory as packages of their own; their route was taken from FDA's record for the same product (labeler and product code).