EFFEXOR XR 150 MG CAPSULE
FDA nonproprietary name: venlafaxine hydrochloride
For 30 capsules
Pharmacies pay
$648.66 filed
30 × $21.62193 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$565.10 filed
30 × $18.83673 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.87× estimated
Medicare paid 13% less than pharmacies pay.
Part D averages every strength and form sold under “Effexor XR” / “Venlafaxine HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$750.96 estimated
$648.66 + $97.30 (15%) + $5.00 fee per fill = $750.96
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
EFFEXOR XR 150 MG CAPSULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as venlafaxine hydrochloride, under the trade name “Effexor XR”.
FDA gives its dosage form as capsule, extended release and its route as oral.
The labeler, the company named on the label, is Viatris Specialty LLC.
FDA’s Established Pharmacologic Class for it is Serotonin and Norepinephrine Reuptake Inhibitor.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $648.66 for 30 capsules (30 × $21.62193 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
NADAC also lists, on the row of its brand NDCs, what pharmacies pay for the generic equivalent, a different product: $0.11901 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · Why 30 capsules · NADAC explanation codes
All 2 NDCs
- 58151-0127-77 · Viatris Specialty LLC · $21.62193 per EA · eff. 2026-09-23 filed
- 58151-0127-93 · Viatris Specialty LLC · $21.62193 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
14 other products in the NADAC file share the FDA nonproprietary name venlafaxine hydrochloride with EFFEXOR XR 150 MG CAPSULE.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| EFFEXOR XR 37.5 MG CAPSULE | $17.70418 per EA filed | $18.83673 per EA filed |
| EFFEXOR XR 75 MG CAPSULE | $19.81997 per EA filed | $18.83673 per EA filed |
| EFFEXOR XR 150 MG CAPSULE this page | $21.62193 per EA filed | $18.83673 per EA filed |
| VENLAFAXINE HCL 25 MG TABLET | $0.07226 per EA filed | $0.27573 per EA filed |
| VENLAFAXINE HCL 37.5 MG TABLET | $0.07145 per EA filed | $0.27573 per EA filed |
| VENLAFAXINE HCL 50 MG TABLET | $0.08941 per EA filed | $0.27573 per EA filed |
| VENLAFAXINE HCL 75 MG TABLET | $0.08507 per EA filed | $0.27573 per EA filed |
| VENLAFAXINE HCL 100 MG TABLET | $0.10992 per EA filed | $0.27573 per EA filed |
| VENLAFAXINE HCL ER 37.5 MG CAP | $0.07912 per EA filed | $0.3469 per EA filed |
| VENLAFAXINE HCL ER 37.5 MG TAB | $0.35811 per EA filed | $0.3469 per EA filed |
| VENLAFAXINE HCL ER 75 MG CAP | $0.07989 per EA filed | $0.3469 per EA filed |
| VENLAFAXINE HCL ER 75 MG TAB | $0.28524 per EA filed | $0.3469 per EA filed |
| VENLAFAXINE HCL ER 150 MG CAP | $0.11901 per EA filed | $0.3469 per EA filed |
| VENLAFAXINE HCL ER 150 MG TAB | $0.22771 per EA filed | $0.3469 per EA filed |
| VENLAFAXINE HCL ER 225 MG TAB | $0.47118 per EA filed | $0.3469 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-09-30 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 2 NDCs’ NADAC prices is $21.62193 per EA filed.
Of the 43 other products in FDA’s Serotonin and Norepinephrine Reuptake Inhibitor class priced per EA, 0 have a higher middle NADAC price and 43 a lower one. The one in the middle is MILNACIPRAN HCL 50 MG TABLET, at $2.80179 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $565.10 for 30 capsules, at an average of $18.83673 per EA in 2024 (2024-01-01 to 2024-12-31) for “Effexor XR” and “Venlafaxine HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 16,997 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: VENLAFAXINE HCL ER 150 MG CAP. Ask your pharmacist or prescriber; do not switch on your own.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for EFFEXOR XR 150 MG CAPSULE labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Effexor XR / Venlafaxine HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
Related pages
Its pharmacologic class
Related in the same class
- DULOXETINE HCL DR 20 MG CAP
- DESVENLAFAXINE SUCCNT ER 100 MG
- SAVELLA 100 MG TABLET
- FETZIMA ER 120 MG CAPSULE
- VENLAFAXINE BES ER 112.5 MG TB