OpenBilldrug price receipt

NADAC week of 2026-10-14

VENLAFAXINE HCL 25 MG TABLET

For 30 tablets

Pharmacies pay

$2.17 filed

30 × $0.07226 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$8.27 filed

30 × $0.27573 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

3.8× estimated

Medicare paid 3.8× what pharmacies pay.

Part D averages every strength and form sold under “Venlafaxine HCl” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$7.50 estimated

$2.17 + $0.33 (15%) + $5.00 fee per fill = $7.50

This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

VENLAFAXINE HCL 25 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “venlafaxine” and “venlafaxine hydrochloride”, as its NDCs’ listings variously write the nonproprietary name.

FDA gives its dosage form as tablet and its route as oral.

FDA lists 8 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals USA, Inc., Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. and Rising Pharma Holdings, Inc.

FDA’s Established Pharmacologic Class for it is Serotonin and Norepinephrine Reuptake Inhibitor.

The NADAC file of 2026-10-14 prices it under 9 NDCs (National Drug Codes); the FDA directory lists 8 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $2.17 for 30 tablets (30 × $0.07226 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

The 8 labelers

LabelerNDCsPharmacies pay per unit
Alembic Pharmaceuticals Inc.1$0.07226 per EA filed
American Health Packaging1$0.07226 per EA filed
BluePoint Laboratories1$0.07226 per EA filed
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.1$0.07226 per EA filed
Rising Pharma Holdings, Inc.1$0.07226 per EA filed
Sun Pharmaceutical Industries, Inc.1$0.07226 per EA filed
Teva Pharmaceuticals USA, Inc.1$0.07226 per EA filed
Zydus Pharmaceuticals USA Inc.1$0.07226 per EA filed
Not listed as a package in the FDA directory1$0.07226 per EA filed
All 9 NDCs, with labeler and price
  • 00093-9147-01 · Teva Pharmaceuticals USA, Inc. · $0.07226 per EA · eff. 2026-09-23 filed
  • 23155-0246-01 · Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. · $0.07226 per EA · eff. 2026-09-23 filed
  • 57237-0172-01 · Rising Pharma Holdings, Inc. · $0.07226 per EA · eff. 2026-09-23 filed
  • 57664-0392-88 · Sun Pharmaceutical Industries, Inc. · $0.07226 per EA · eff. 2026-09-23 filed
  • 62332-0008-31 · Alembic Pharmaceuticals Inc. · $0.07226 per EA · eff. 2026-09-23 filed
  • 68001-0157-00 · BluePoint Laboratories · $0.07226 per EA · eff. 2026-09-23 filed
  • 68084-0896-25 · American Health Packaging · $0.07226 per EA · eff. 2026-09-23 filed
  • 68084-0896-95 · not listed as a package in the FDA directory · $0.07226 per EA · eff. 2026-09-23 filed
  • 68382-0018-01 · Zydus Pharmaceuticals USA Inc. · $0.07226 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

15 other products in the NADAC file share an FDA nonproprietary name with VENLAFAXINE HCL 25 MG TABLET.

ProductPharmacies pay per unitMedicare per unit
EFFEXOR XR 37.5 MG CAPSULE
brand · capsule, extended release
$17.70418 per EA filed
eff. 2026-09-23
$18.83673 per EA filed
Part D 2024 average
EFFEXOR XR 75 MG CAPSULE
brand · capsule, extended release
$19.81997 per EA filed
eff. 2026-09-23
$18.83673 per EA filed
Part D 2024 average
EFFEXOR XR 150 MG CAPSULE
brand · capsule, extended release
$21.62193 per EA filed
eff. 2026-09-23
$18.83673 per EA filed
Part D 2024 average
VENLAFAXINE BES ER 112.5 MG TB
generic · tablet, extended release
$6.22984 per EA filed
eff. 2026-09-23
We don’t know yet
VENLAFAXINE HCL 25 MG TABLET this page
generic · tablet
$0.07226 per EA filed
eff. 2026-09-23
$0.27573 per EA filed
Part D 2024 average
VENLAFAXINE HCL 37.5 MG TABLET
generic · tablet
$0.07145 per EA filed
eff. 2026-09-23
$0.27573 per EA filed
Part D 2024 average
VENLAFAXINE HCL 50 MG TABLET
generic · tablet
$0.08941 per EA filed
eff. 2026-09-23
$0.27573 per EA filed
Part D 2024 average
VENLAFAXINE HCL 75 MG TABLET
generic · tablet
$0.08507 per EA filed
eff. 2026-09-23
$0.27573 per EA filed
Part D 2024 average
VENLAFAXINE HCL 100 MG TABLET
generic · tablet
$0.10992 per EA filed
eff. 2026-09-23
$0.27573 per EA filed
Part D 2024 average
VENLAFAXINE HCL ER 37.5 MG CAP
generic · capsule, extended release
$0.07912 per EA filed
eff. 2026-09-23 to 2026-09-30
$0.3469 per EA filed
Part D 2024 average
VENLAFAXINE HCL ER 37.5 MG TAB
generic · tablet, extended release
$0.35811 per EA filed
eff. 2026-09-23
$0.3469 per EA filed
Part D 2024 average
VENLAFAXINE HCL ER 75 MG CAP
generic · capsule, extended release
$0.07989 per EA filed
eff. 2026-09-23 to 2026-09-30
$0.3469 per EA filed
Part D 2024 average
VENLAFAXINE HCL ER 75 MG TAB
generic · tablet, extended release / tablet, coated
$0.28524 per EA filed
eff. 2026-09-23
$0.3469 per EA filed
Part D 2024 average
VENLAFAXINE HCL ER 150 MG CAP
generic · capsule, extended release
$0.11901 per EA filed
eff. 2026-09-23 to 2026-09-30
$0.3469 per EA filed
Part D 2024 average
VENLAFAXINE HCL ER 150 MG TAB
generic · tablet, extended release / tablet / tablet, coated
$0.22771 per EA filed
eff. 2026-09-23
$0.3469 per EA filed
Part D 2024 average
VENLAFAXINE HCL ER 225 MG TAB
generic · tablet, extended release / tablet / tablet, coated
$0.47118 per EA filed
eff. 2026-09-23
$0.3469 per EA filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-09-30 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 9 NDCs’ NADAC prices is $0.07226 per EA filed.

Of the 43 other products in FDA’s Serotonin and Norepinephrine Reuptake Inhibitor class priced per EA, 42 have a higher middle NADAC price and 1 a lower one. The one in the middle is MILNACIPRAN HCL 100 MG TABLET, at $2.81889 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $8.27 for 30 tablets, at an average of $0.27573 per EA in 2024 (2024-01-01 to 2024-12-31) for “Venlafaxine HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 731,696 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for VENLAFAXINE HCL 25 MG TABLET labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Venlafaxine HCl / Venlafaxine HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.