ENTRESTO SPRINKLE 6-6 MG PELLET
FDA nonproprietary name: sacubitril and valsartan
For 1 unit (EA)
Pharmacies pay
$11.62 filed
1 × $11.6248 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$18.36 estimated
$11.62 + $1.74 (15%) + $5.00 fee per fill = $18.36
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
ENTRESTO SPRINKLE 6-6 MG PELLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as sacubitril and valsartan, under the trade name “ENTRESTO”.
FDA gives its dosage form as pellet and its route as oral.
The labeler, the company named on the label, is Novartis Pharmaceuticals Corporation.
FDA lists it under 2 Established Pharmacologic Classes: Angiotensin 2 Receptor Blocker and Neprilysin Inhibitor.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00078-1231-20.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $11.62 for 1 unit (EA) (1 × $11.6248 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · NADAC explanation codes
The NDC
- 00078-1231-20 · Novartis Pharmaceuticals Corporation · $11.6248 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
7 other products in the NADAC file share the FDA nonproprietary name sacubitril and valsartan with ENTRESTO SPRINKLE 6-6 MG PELLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ENTRESTO 24 MG-26 MG TABLET | $11.5927 per EA filed | $11.03995 per EA filed |
| ENTRESTO 49 MG-51 MG TABLET | $11.56059 per EA filed | $11.03995 per EA filed |
| ENTRESTO 97 MG-103 MG TABLET | $11.58867 per EA filed | $11.03995 per EA filed |
| ENTRESTO SPRINKLE 6-6 MG PELLET this page | $11.6248 per EA filed | We don’t know yet |
| ENTRESTO SPRINKLE 15-16 MG PLT | $11.60672 per EA filed | We don’t know yet |
| SACUBITRIL-VALSARTAN 24-26 MG | $0.49855 per EA filed | We don’t know yet |
| SACUBITRIL-VALSARTAN 49-51 MG | $0.53337 per EA filed | We don’t know yet |
| SACUBITRIL-VALSARTAN 97-103 MG | $0.59213 per EA filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $11.6248 per EA filed.
Of the 107 other products in FDA’s Angiotensin 2 Receptor Blocker class priced per EA, 12 have a higher middle NADAC price and 95 a lower one. The one in the middle is CANDESARTAN-HYDROCHLOROTHIAZIDE 32-25 MG TAB, at $1.07781 per EA filed (eff. 2026-09-23).
Of the 7 other products in FDA’s Neprilysin Inhibitor class priced per EA, 0 have a higher middle NADAC price and 7 a lower one. The one in the middle is ENTRESTO 49 MG-51 MG TABLET, at $11.56059 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 unit (EA)?
- NADAC prices this product per EA, and the FDA NDC Directory lists its NDC as dosage form “PELLET” with route “ORAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.
Related pages
Its pharmacologic classes
Related in the same class
- LOSARTAN POTASSIUM 100 MG TAB
- LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB
- VALSARTAN 160 MG TABLET
- OLMESARTAN MEDOXOMIL 20 MG TAB
- IRBESARTAN 150 MG TABLET