SACUBITRIL-VALSARTAN 49-51 MG
For 30 tablets
Pharmacies pay
$16.00 filed
30 × $0.53337 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$23.40 estimated
$16.00 + $2.40 (15%) + $5.00 fee per fill = $23.40
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
SACUBITRIL-VALSARTAN 49-51 MG is how the CMS NADAC file names this product. The FDA NDC Directory lists it as sacubitril and valsartan, under the trade name “Sacubitril and Valsartan Sacubitril and Valsartan”.
FDA gives its dosage form as “tablet, film coated” and “tablet” and its route as oral.
FDA lists 16 labelers (the companies named on the label) for its NDCs, among them Major Pharmaceuticals, Torrent Pharmaceuticals Limited and Camber Pharmaceuticals, Inc.
FDA lists it under 2 Established Pharmacologic Classes: Angiotensin 2 Receptor Blocker and Neprilysin Inhibitor.
The NADAC file of 2026-10-14 prices it under 32 NDCs (National Drug Codes); the FDA directory lists 30 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $16.00 for 30 tablets (30 × $0.53337 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 16 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Torrent Pharmaceuticals Limited | 4 | $0.53337 per EA filed |
| Ascend Laboratories, LLC | 3 | $0.53337 per EA filed |
| ANI Pharmaceuticals, Inc. | 2 | $0.53337 per EA filed |
| Alembic Pharmaceuticals Inc. | 2 | $0.53337 per EA filed |
| Amneal Pharmaceuticals NY LLC | 2 | $0.53337 per EA filed |
| Biocon Pharma Inc. | 2 | $0.53337 per EA filed |
| Camber Pharmaceuticals, Inc. | 2 | $0.53337 per EA filed |
| Dr. Reddy's Laboratories Inc. | 2 | $0.53337 per EA filed |
| Macleods Pharmaceuticals Limited | 2 | $0.53337 per EA filed |
| Novadoz Pharmaceuticals LLC | 2 | $0.53337 per EA filed |
| Novugen Pharma (USA) LLC | 2 | $0.53337 per EA filed |
| American Health Packaging | 1 | $0.53337 per EA filed |
| AvPAK | 1 | $0.53337 per EA filed |
| Lupin Pharmaceuticals, Inc. | 1 | $0.53337 per EA filed |
| Major Pharmaceuticals | 1 | $0.53337 per EA filed |
| Zydus Pharmaceuticals USA Inc. | 1 | $0.53337 per EA filed |
| Not listed as a package in the FDA directory | 2 | $0.53337 per EA filed |
All 32 NDCs, with labeler and price
- 00904-7582-04 · Major Pharmaceuticals · $0.53337 per EA · eff. 2026-09-23 filed
- 13668-0635-33 · Torrent Pharmaceuticals Limited · $0.53337 per EA · eff. 2026-09-23 filed
- 13668-0635-60 · Torrent Pharmaceuticals Limited · $0.53337 per EA · eff. 2026-09-23 filed
- 13668-0746-33 · Torrent Pharmaceuticals Limited · $0.53337 per EA · eff. 2026-09-23 filed
- 13668-0746-60 · Torrent Pharmaceuticals Limited · $0.53337 per EA · eff. 2026-09-23 filed
- 31722-0674-18 · Camber Pharmaceuticals, Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 31722-0674-60 · Camber Pharmaceuticals, Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 33342-0571-09 · Macleods Pharmaceuticals Limited · $0.53337 per EA · eff. 2026-09-23 filed
- 33342-0571-57 · Macleods Pharmaceuticals Limited · $0.53337 per EA · eff. 2026-09-23 filed
- 43598-0644-18 · Dr. Reddy's Laboratories Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 43598-0644-60 · Dr. Reddy's Laboratories Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 50268-0607-11 · not listed as a package in the FDA directory · $0.53337 per EA · eff. 2026-09-23 filed
- 50268-0607-15 · AvPAK · $0.53337 per EA · eff. 2026-09-23 filed
- 60687-0966-11 · not listed as a package in the FDA directory · $0.53337 per EA · eff. 2026-09-23 filed
- 60687-0966-57 · American Health Packaging · $0.53337 per EA · eff. 2026-09-23 filed
- 62332-0557-45 · Alembic Pharmaceuticals Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 62332-0557-60 · Alembic Pharmaceuticals Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 67877-0708-60 · Ascend Laboratories, LLC · $0.53337 per EA · eff. 2026-09-23 filed
- 67877-0949-51 · Ascend Laboratories, LLC · $0.53337 per EA · eff. 2026-09-23 filed
- 67877-0949-60 · Ascend Laboratories, LLC · $0.53337 per EA · eff. 2026-09-23 filed
- 69238-2732-01 · Amneal Pharmaceuticals NY LLC · $0.53337 per EA · eff. 2026-09-23 filed
- 69238-2732-02 · Amneal Pharmaceuticals NY LLC · $0.53337 per EA · eff. 2026-09-23 filed
- 70377-0032-12 · Biocon Pharma Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 70377-0032-13 · Biocon Pharma Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 70710-1273-06 · Zydus Pharmaceuticals USA Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 70748-0196-07 · Lupin Pharmaceuticals, Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 70954-0976-20 · ANI Pharmaceuticals, Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 70954-0976-30 · ANI Pharmaceuticals, Inc. · $0.53337 per EA · eff. 2026-09-23 filed
- 72205-0281-18 · Novadoz Pharmaceuticals LLC · $0.53337 per EA · eff. 2026-09-23 filed
- 72205-0281-60 · Novadoz Pharmaceuticals LLC · $0.53337 per EA · eff. 2026-09-23 filed
- 82293-0028-10 · Novugen Pharma (USA) LLC · $0.53337 per EA · eff. 2026-09-23 filed
- 82293-0028-20 · Novugen Pharma (USA) LLC · $0.53337 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
7 other products in the NADAC file share the FDA nonproprietary name sacubitril and valsartan with SACUBITRIL-VALSARTAN 49-51 MG.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ENTRESTO 24 MG-26 MG TABLET | $11.5927 per EA filed | $11.03995 per EA filed |
| ENTRESTO 49 MG-51 MG TABLET | $11.56059 per EA filed | $11.03995 per EA filed |
| ENTRESTO 97 MG-103 MG TABLET | $11.58867 per EA filed | $11.03995 per EA filed |
| ENTRESTO SPRINKLE 6-6 MG PELLET | $11.6248 per EA filed | We don’t know yet |
| ENTRESTO SPRINKLE 15-16 MG PLT | $11.60672 per EA filed | We don’t know yet |
| SACUBITRIL-VALSARTAN 24-26 MG | $0.49855 per EA filed | We don’t know yet |
| SACUBITRIL-VALSARTAN 49-51 MG this page | $0.53337 per EA filed | We don’t know yet |
| SACUBITRIL-VALSARTAN 97-103 MG | $0.59213 per EA filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 32 NDCs’ NADAC prices is $0.53337 per EA filed.
Of the 107 other products in FDA’s Angiotensin 2 Receptor Blocker class priced per EA, 64 have a higher middle NADAC price and 43 a lower one. The one in the middle is OLMSRTN-AMLDPN-HYDROCHLOROTHIAZIDE 40-10-12.5, at $1.15137 per EA filed (eff. 2026-09-23).
Of the 7 other products in FDA’s Neprilysin Inhibitor class priced per EA, 6 have a higher middle NADAC price and 1 a lower one. The one in the middle is ENTRESTO 97 MG-103 MG TABLET, at $11.58867 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Related pages
Its pharmacologic classes
Related in the same class
- LOSARTAN POTASSIUM 100 MG TAB
- LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB
- VALSARTAN 160 MG TABLET
- OLMESARTAN MEDOXOMIL 20 MG TAB
- IRBESARTAN 150 MG TABLET