OpenBilldrug price receipt

NADAC week of 2026-10-14

ENULOSE 10 GM/15 ML SOLUTION

FDA nonproprietary name: lactulose

For 473 mL

Pharmacies pay

$6.17 filed

473 × $0.01304 per ML

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$12.65 filed

473 × $0.02674 per ML, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

2.1× estimated

Medicare paid 2.1× what pharmacies pay.

Part D averages every strength and form sold under “Enulose” / “Lactulose” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$12.10 estimated

$6.17 + $0.93 (15%) + $5.00 fee per fill = $12.10

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

ENULOSE 10 GM/15 ML SOLUTION is how the CMS NADAC file names this product. The FDA NDC Directory lists it as lactulose, under the trade name “Enulose”.

FDA gives its dosage form as solution and its route as oral; rectal.

The labeler, the company named on the label, is Actavis Pharma, Inc.

FDA’s Established Pharmacologic Class for it is Osmotic Laxative.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 45963-0438-64.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $6.17 for 473 mL (473 × $0.01304 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

The NDC

Other strengths, forms and brands

8 other products in the NADAC file share the FDA nonproprietary name lactulose with ENULOSE 10 GM/15 ML SOLUTION.

ProductPharmacies pay per unitMedicare per unit
CONSTULOSE 10 GM/15 ML SOLN
generic · solution
$0.01939 to $0.01947 per ML filed
eff. 2026-09-23
$0.01987 per ML filed
Part D 2024 average
ENULOSE 10 GM/15 ML SOLUTION this page
generic · solution
$0.01304 per ML filed
eff. 2026-09-23
$0.02674 per ML filed
Part D 2024 average
GENERLAC 10 GM/15 ML SOLUTION
generic · solution
$0.01304 per ML filed
eff. 2026-09-23
$0.02239 per ML filed
Part D 2024 average
KRISTALOSE 10 GM PACKET
brand · powder, for solution
$9.59114 per EA filed
eff. 2026-09-23
$9.71754 per EA filed
Part D 2024 average
KRISTALOSE 20 GM PACKET
brand · powder, for solution
$9.96221 per EA filed
eff. 2026-09-23
$9.71754 per EA filed
Part D 2024 average
LACTULOSE 10 GM PACKET
generic · powder, for solution
$8.22014 per EA filed
eff. 2026-09-23
We don’t know yet
LACTULOSE 10 GM/15 ML SOLUTION
generic · solution
$0.0125 to $0.02237 per ML filed
eff. 2026-09-23
We don’t know yet
LACTULOSE 20 GM PACKET
generic · powder, for solution
$8.51402 per EA filed
eff. 2026-09-23
We don’t know yet
LACTULOSE 20 GM/30 ML SOLUTION CUP
generic · solution
$0.0512 per ML filed
eff. 2026-02-18
We don’t know yet

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-02-18, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

Its NADAC price is $0.01304 per ML filed.

Of the 38 other products in FDA’s Osmotic Laxative class priced per ML, 14 have a higher middle NADAC price and 23 a lower one; 1 has the same. The one in the middle is ANTACID ANTI-GAS LIQUID, at $0.01206 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $12.65 for 473 mL, at an average of $0.02674 per ML in 2024 (2024-01-01 to 2024-12-31) for “Enulose” and “Lactulose”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 236,911 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for ENULOSE 10 GM/15 ML SOLUTION labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Enulose / Lactulose: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on brand name.
Why does this page start at 473 mL?
NADAC prices this product per ML. The FDA NDC Directory’s package description gives 473 mL in one package for this product’s NDC (“473 mL in 1 BOTTLE (45963-438-64)”), so the card starts at one package: 473 ML. Change it to match your prescription.