KRISTALOSE 20 GM PACKET

What it is

KRISTALOSE 20 GM PACKET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as lactulose, under the trade name “KRISTALOSE”.

FDA gives its dosage form as powder, for solution and its route as oral.

The labeler, the company named on the label, is Cumberland Pharmaceuticals Inc.

FDA’s Established Pharmacologic Class for it is Osmotic Laxative.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes); the FDA directory lists 1 of them.

NADAC classes it in its brand rate-setting class B-ANDA, and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $9.96 for 1 unit (EA) (1 × $9.96221 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

NADAC also lists, on the row of its brand NDCs, what pharmacies pay for the generic equivalent, a different product: $8.51402 per EA filed.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What NADAC measures · NADAC explanation codes

All 2 NDCs

• 66220-0729-01 · not listed as a package in the FDA directory · $9.96221 per EA · eff. 2026-09-23 filed
• 66220-0729-30 · Cumberland Pharmaceuticals Inc. · $9.96221 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

8 other products in the NADAC file share the FDA nonproprietary name lactulose with KRISTALOSE 20 GM PACKET.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-02-18, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $9.96221 per EA filed.

Of the 43 other products in FDA’s Osmotic Laxative class priced per EA, 3 have a higher middle NADAC price and 40 a lower one. The one in the middle is KLOR-CON M15 TABLET, at $0.49604 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $9.72 for 1 unit (EA), at an average of $9.71754 per EA in 2024 (2024-01-01 to 2024-12-31) for “Kristalose” and “Lactulose”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 6,944 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
• Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: LACTULOSE 20 GM PACKET. Ask your pharmacist or prescriber; do not switch on your own.
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.