OpenBilldrug price receipt

NADAC week of 2026-10-14

EPIDUO FORTE 0.3-2.5% GEL PUMP

FDA nonproprietary name: adapalene and benzoyl peroxide

For 45 g

Pharmacies pay

$673.52 filed

45 × $14.9672 per GM

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$673.67 filed

45 × $14.97049 per GM, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

1.0× estimated

Medicare paid about what pharmacies pay.

Part D averages every strength and form sold under “Epiduo Forte” / “Adapalene/Benzoyl Peroxide” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$779.55 estimated

$673.52 + $101.03 (15%) + $5.00 fee per fill = $779.55

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

EPIDUO FORTE 0.3-2.5% GEL PUMP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as adapalene and benzoyl peroxide, under the trade name “epiduo forte”.

FDA gives its dosage form as gel and its route as topical.

The labeler, the company named on the label, is Galderma Laboratories, L.P.

FDA’s Established Pharmacologic Class for it is Retinoid.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00299-5906-45.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $673.52 for 45 g (45 × $14.9672 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $0.62604 per GM filed.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

The NDC

Other strengths, forms and brands

2 other products in the NADAC file share the FDA nonproprietary name adapalene and benzoyl peroxide with EPIDUO FORTE 0.3-2.5% GEL PUMP.

ProductPharmacies pay per unitMedicare per unit
ADAPALENE-BNZYL PEROX 0.1-2.5%
generic · gel
$0.36818 per GM filed
eff. 2026-09-23
$1.84866 per GM filed
Part D 2024 average
ADAPALENE-BNZYL PEROX 0.3-2.5%
generic · gel
$0.62604 per GM filed
eff. 2026-09-23
$1.84866 per GM filed
Part D 2024 average
EPIDUO FORTE 0.3-2.5% GEL PUMP this page
brand · gel
$14.9672 per GM filed
eff. 2026-09-23
$14.97049 per GM filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

Its NADAC price is $14.9672 per GM filed.

Of the 23 other products in FDA’s Retinoid class priced per GM, 2 have a higher middle NADAC price and 21 a lower one. The one in the middle is TRETINOIN 0.025% GEL, at $2.50019 per GM filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $673.67 for 45 g, at an average of $14.97049 per GM in 2024 (2024-01-01 to 2024-12-31) for “Epiduo Forte” and “Adapalene/Benzoyl Peroxide”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 87 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for EPIDUO FORTE 0.3-2.5% GEL PUMP labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Epiduo Forte / Adapalene/Benzoyl Peroxide: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on brand name.
Why does this page start at 45 g?
NADAC prices this product per GM. The FDA NDC Directory’s package description gives 45 g in one package for this product’s NDC (“1 BOTTLE, PUMP in 1 CARTON (0299-5906-45) / 45 g in 1 BOTTLE, PUMP”), so the card starts at one package: 45 GM. Change it to match your prescription.