OpenBilldrug price receipt

NADAC week of 2026-10-14

ADAPALENE-BNZYL PEROX 0.3-2.5%

For 45 g

Pharmacies pay

$28.17 filed

45 × $0.62604 per GM

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$83.19 filed

45 × $1.84866 per GM, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

The spread

3.0× estimated

Medicare paid 3.0× what pharmacies pay.

Part D averages every strength and form sold under “Adapalene-Benzoyl Peroxide” / “Adapalene/Benzoyl Peroxide” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$37.40 estimated

$28.17 + $4.23 (15%) + $5.00 fee per fill = $37.40

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

ADAPALENE-BNZYL PEROX 0.3-2.5% is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “adapalene and benzoyl peroxide” and “adapalene and benzoyl peroxide topical”, as its NDCs’ listings variously write the nonproprietary name.

FDA gives its dosage form as gel and its route as topical.

FDA lists 6 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals, Inc., Padagis Israel Pharmaceuticals Ltd and Sun Pharmaceutical Industries, Inc.

FDA’s Established Pharmacologic Class for it is Retinoid.

The NADAC file of 2026-10-14 prices it under 6 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $28.17 for 45 g (45 × $0.62604 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

What NADAC measures · NADAC explanation codes

All 6 NDCs

Other strengths, forms and brands

2 other products in the NADAC file share an FDA nonproprietary name with ADAPALENE-BNZYL PEROX 0.3-2.5%.

ProductPharmacies pay per unitMedicare per unit
ADAPALENE-BNZYL PEROX 0.1-2.5%
generic · gel		$0.36818 per GM filed
eff. 2026-09-23		$1.84866 per GM filed
Part D 2024 average
ADAPALENE-BNZYL PEROX 0.3-2.5% this page
generic · gel		$0.62604 per GM filed
eff. 2026-09-23		$1.84866 per GM filed
Part D 2024 average
EPIDUO FORTE 0.3-2.5% GEL PUMP
brand · gel		$14.9672 per GM filed
eff. 2026-09-23		$14.97049 per GM filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 6 NDCs’ NADAC prices is $0.62604 per GM filed.

Of the 23 other products in FDA’s Retinoid class priced per GM, 18 have a higher middle NADAC price and 5 a lower one. The one in the middle is ADAPALENE 0.1% CREAM, at $2.85454 per GM filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $83.19 for 45 g, at an average of $1.84866 per GM in 2024 (2024-01-01 to 2024-12-31) for “Adapalene-Benzoyl Peroxide” and “Adapalene/Benzoyl Peroxide”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 2,006 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for ADAPALENE-BNZYL PEROX 0.3-2.5% labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Adapalene-Benzoyl Peroxide / Adapalene/Benzoyl Peroxide: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on generic name.
Why does this page start at 45 g?
NADAC prices this product per GM. The FDA NDC Directory’s package description gives 45 g in one package for all 6 NDCs of this product (“1 BOTTLE, PUMP in 1 CARTON (0480-3154-45) / 45 g in 1 BOTTLE, PUMP”), so the card starts at one package: 45 GM. Change it to match your prescription.

Its pharmacologic class

Related in the same class

More