GENGRAF 25 MG CAPSULE
FDA nonproprietary name: cyclosporine
For 30 capsules
Pharmacies pay
$55.96 filed
30 × $1.86549 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-02 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$34.28 filed
30 × $1.14257 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.61× estimated
Medicare paid 39% less than pharmacies pay.
Part D averages every strength and form sold under “Gengraf” / “Cyclosporine, Modified” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-01-02 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$69.35 estimated
$55.96 + $8.39 (15%) + $5.00 fee per fill = $69.35
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-01-02 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
GENGRAF 25 MG CAPSULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as cyclosporine, under the trade name “Gengraf”.
FDA gives its dosage form as capsule and its route as oral.
The labeler, the company named on the label, is AbbVie Inc.
FDA’s Established Pharmacologic Class for it is Calcineurin Inhibitor Immunosuppressant.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00074-3108-32.
NADAC classes it in its brand rate-setting class B-ANDA, and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $55.96 for 30 capsules (30 × $1.86549 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-01-02. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 4, carried forward from the previous file; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-01-02. The file is new; the price is not.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $0.31377 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · Why 30 capsules · NADAC explanation codes · Carried-forward prices
The NDC
- 00074-3108-32 · AbbVie Inc. · $1.86549 per EA · eff. 2026-01-02 filed carried forward
Other strengths, forms and brands
12 other products in the NADAC file share the FDA nonproprietary name cyclosporine with GENGRAF 25 MG CAPSULE.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CEQUA 0.09% SOLUTION | $10.38279 per EA filed | $9.33517 per EA filed |
| CYCLOSPORINE 0.05% EYE EMULSION | $0.90945 to $1.18033 per EA filed | $4.32927 per EA filed |
| CYCLOSPORINE 25 MG CAPSULE | $2.5957 per EA filed | $0.576 per EA derived |
| CYCLOSPORINE 100 MG CAPSULE | $7.50676 per EA filed | $1.455 per EA derived |
| CYCLOSPORINE MODIFIED 25 MG | $0.31377 per EA filed | $0.576 per EA derived |
| CYCLOSPORINE MODIFIED 50 MG | $0.76459 per EA filed | $0.7275 to $1.152 per EA derived |
| CYCLOSPORINE MODIFIED 100 MG | $1.23348 per EA filed | $1.455 per EA derived |
| CYCLOSPORINE MODIFIED 100 MG/ML | $2.03685 per ML filed | $1.455 per ML derived |
| GENGRAF 25 MG CAPSULE this page | $1.86549 per EA filed | $1.14257 per EA filed |
| NEORAL 25 MG GELATIN CAPSULE | $2.94566 per EA filed | $3.90784 per EA filed |
| NEORAL 100 MG GELATIN CAPSULE | $11.7731 per EA filed | $3.90784 per EA filed |
| RESTASIS 0.05% EYE EMULSION | $10.31247 to $10.31333 per EA filed | $10.19841 per EA filed |
| RESTASIS MULTIDOSE 0.05% EYE | $112.32159 per ML filed | $111.93625 per ML filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-02, 2026-07-08, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
Its NADAC price is $1.86549 per EA filed.
Of the 19 other products in FDA’s Calcineurin Inhibitor Immunosuppressant class priced per EA, 12 have a higher middle NADAC price and 7 a lower one. The one in the middle is NEORAL 25 MG GELATIN CAPSULE, at $2.94566 per EA filed (eff. 2026-07-08).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-02, 2026-07-08 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $34.28 for 30 capsules, at an average of $1.14257 per EA in 2024 (2024-01-01 to 2024-12-31) for “Gengraf” and “Cyclosporine, Modified”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 4,222 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for GENGRAF 25 MG CAPSULE labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Gengraf / Cyclosporine, Modified: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
Related pages
Its pharmacologic class
Related in the same class
- PIMECROLIMUS 1% CREAM
- VEVYE 0.1% EYE DROP
- ASTAGRAF XL 0.5 MG CAPSULE
- TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)