HUMALOG MIX 75-25 KWIKPEN
FDA nonproprietary name: insulin lispro
For 15 mL
Pharmacies pay
$152.50 filed
15 × $10.1667 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$180.38 estimated
$152.50 + $22.88 (15%) + $5.00 fee per fill = $180.38
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
HUMALOG MIX 75-25 KWIKPEN is how the CMS NADAC file names this product. The FDA NDC Directory lists it as insulin lispro, under the trade name “Humalog Mix75/25 KwikPen”.
FDA gives its dosage form as injection, suspension and its route as subcutaneous.
The labeler, the company named on the label, is Eli Lilly and Company.
FDA’s Established Pharmacologic Class for it is Insulin Analog.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00002-8797-59.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $152.50 for 15 mL (15 × $10.1667 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The NDC
- 00002-8797-59 · Eli Lilly and Company · $10.1667 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
14 other products in the NADAC file share the FDA nonproprietary name insulin lispro with HUMALOG MIX 75-25 KWIKPEN.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ADMELOG 100 UNIT/ML VIAL | $9.39379 to $12.56125 per ML filed | $9.7762 per ML filed |
| ADMELOG SOLOSTAR 100 UNIT/ML | $12.10918 per ML filed | $6.232 per ML derived |
| HUMALOG 100 UNIT/ML CARTRIDGE | $9.78555 per ML filed | $6.18454 per ML filed |
| HUMALOG 100 UNIT/ML KWIKPEN | $10.16762 per ML filed | $9.91201 per ML filed |
| HUMALOG 100 UNIT/ML VIAL | $6.35737 per ML filed | $6.18454 per ML filed |
| HUMALOG 200 UNIT/ML KWIKPEN | $20.31012 per ML filed | $65.66237 per ML filed |
| HUMALOG JR 100 UNIT/ML KWIKPEN | $10.15829 per ML filed | $9.9833 per ML filed |
| HUMALOG MIX 50-50 KWIKPEN | $10.14137 per ML filed | We don’t know yet |
| HUMALOG MIX 75-25 KWIKPEN this page | $10.1667 per ML filed | We don’t know yet |
| HUMALOG MIX 75-25 VIAL | $8.15257 per ML filed | We don’t know yet |
| HUMALOG TEMPO PEN 100 UNIT/ML | $10.12721 per ML filed | $6.232 per ML derived |
| INSULIN LISPRO 100 UNIT/ML KWIKPEN | $10.19333 per ML filed | $10.20103 per ML filed |
| INSULIN LISPRO 100 UNIT/ML VL | $2.40265 per ML filed | $2.49228 per ML filed |
| INSULIN LISPRO JR 100 UNIT/ML KWIKPEN | $10.19937 per ML filed | $10.08062 per ML filed |
| INSULIN LISPRO MIX 75-25 KWKPN | $10.20743 per ML filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-06-17, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
Its NADAC price is $10.1667 per ML filed.
Of the 56 other products in FDA’s Insulin Analog class priced per ML, 21 have a higher middle NADAC price and 35 a lower one. The one in the middle is TRESIBA FLEXTOUCH 100 UNIT/ML, at $9.03577 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 15 mL? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: INSULIN LISPRO MIX 75-25 KWKPN. Ask your pharmacist or prescriber; do not switch on your own.
- How much is in the package I am getting? This page uses 15 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 15 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 15 mL in one package for this product’s NDC (“5 SYRINGE in 1 CARTON (0002-8797-59) / 3 mL in 1 SYRINGE (0002-8797-01)”), so the card starts at one package: 15 ML. Change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- LANTUS SOLOSTAR 100 UNIT/ML
- TRESIBA FLEXTOUCH 100 UNIT/ML
- FIASP 100 UNIT/ML FLEXTOUCH
- SOLIQUA 100 UNIT-33 MCG/ML PEN
- LYUMJEV 100 UNIT/ML KWIKPEN