ISOTRETINOIN 20 MG CAPSULE

What it is

ISOTRETINOIN 20 MG CAPSULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as isotretinoin.

FDA gives its dosage form as “capsule, liquid filled” and “capsule” and its route as oral.

FDA lists 7 labelers (the companies named on the label) for its NDCs, among them Upsher-Smith Laboratories, LLC, Actavis Pharma, Inc. and Sun Pharmaceutical Industries, Inc.

FDA’s Established Pharmacologic Class for it is Retinoid.

The NADAC file of 2026-10-14 prices it under 18 NDCs (National Drug Codes); the FDA directory lists 10 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $57.97 – $127.62 for 30 capsules, depending on the NDC ($1.93248 to $4.25389 per EA), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

What NADAC measures · Why 30 capsules · NADAC explanation codes

The 7 labelers

Other strengths, forms and brands

22 other products in the NADAC file share the FDA nonproprietary name isotretinoin with ISOTRETINOIN 20 MG CAPSULE.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. between 2025-12-17 and 2026-09-23 (5 dates) · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 18 NDCs’ NADAC prices is $4.25389 per EA filed.

Of the 26 other products in FDA’s Retinoid class priced per EA, 12 have a higher middle NADAC price and 14 a lower one. The one in the middle is ACITRETIN 10 MG CAPSULE, at $2.59463 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $132.15 for 30 capsules, at an average of $4.4049 per EA in 2024 (2024-01-01 to 2024-12-31) for “Isotretinoin”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 7,711 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
• Which NDC (the 11-digit number on the package) is this? Pharmacies pay $1.93248 to $4.25389 per EA for this product, depending on the NDC.
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.