JUBBONTI 60 MG/ML SYRINGE
FDA nonproprietary name: denosumab
For 1 mL
Pharmacies pay
$1,536.91 filed
1 × $1,536.90512 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$1,619.46 derived
1 × $1,619.46 per ML, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
1.1× estimated
Medicare pays 1.1× what pharmacies pay.
Only one labeler, Sandoz Inc., is listed for HCPCS Q5136 on the CMS crosswalk, but the payment limit file’s Notes for the code say “8% of reference add-on applied”, so the limit is not worked out from that company’s own sales price alone.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$1,772.45 estimated
$1,536.91 + $230.54 (15%) + $5.00 fee per fill = $1,772.45
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
JUBBONTI 60 MG/ML SYRINGE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as denosumab, under the trade name “JUBBONTI”.
FDA gives its dosage form as injection and its route as subcutaneous.
The labeler, the company named on the label, is Sandoz Inc.
FDA’s Established Pharmacologic Class for it is RANK Ligand Inhibitor.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 61314-0240-63.
NADAC classes it in its brand rate-setting class B-BIO, and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1,536.91 for 1 mL (1 × $1,536.90512 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The NDC
- 61314-0240-63 · Sandoz Inc · $1,536.90512 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
4 other products in the NADAC file share the FDA nonproprietary name denosumab with JUBBONTI 60 MG/ML SYRINGE.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| BILDYOS 60 MG/ML SYRINGE | $814.13419 per ML filed | $920.16 per ML derived |
| CONEXXENCE 60 MG/ML SYRINGE | $1,740.44875 per ML filed | $1,722.12 per ML derived |
| JUBBONTI 60 MG/ML SYRINGE this page | $1,536.90512 per ML filed | $1,619.46 per ML derived |
| PROLIA 60 MG/ML SYRINGE | $1,862.74398 per ML filed | $1,711.37983 per ML filed |
| XGEVA 120 MG/1.7 ML VIAL | $2,001.51678 per ML filed | $1,850.82154 per ML filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-07, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
Its NADAC price is $1,536.90512 per ML filed.
Of the 5 other products in FDA’s RANK Ligand Inhibitor class priced per ML, 4 have a higher middle NADAC price and 1 a lower one. The one in the middle is CONEXXENCE 60 MG/ML SYRINGE, at $1,740.44875 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part B’s payment limit for HCPCS Q5136, for 2026-10-01 to 2026-12-31, comes to $1,619.46 for 1 mL, or $1,619.46 per ML once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $5.3982 per 1 MG.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 1 mL in one package for this product’s NDC (“1 SYRINGE in 1 CARTON (61314-240-63) / 1 mL in 1 SYRINGE”), so the card starts at one package: 1 ML. Change it to match your prescription.