OpenBilldrug price receipt

NADAC week of 2026-10-14

LUBIPROSTONE 8 MCG CAPSULE

For 30 capsules

Pharmacies pay

$16.96 filed

30 × $0.56517 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$50.03 filed

30 × $1.66781 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

3.0× estimated

Medicare paid 3.0× what pharmacies pay.

Part D averages every strength and form sold under “Lubiprostone” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$24.50 estimated

$16.96 + $2.54 (15%) + $5.00 fee per fill = $24.50

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

LUBIPROSTONE 8 MCG CAPSULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as lubiprostone.

FDA gives its dosage form as “capsule, gelatin coated” and “capsule” and its route as oral.

FDA lists 9 labelers (the companies named on the label) for its NDCs, among them Par Health USA, LLC, Teva Pharmaceuticals, Inc. and Camber Pharmaceuticals, Inc.

FDA’s Established Pharmacologic Class for it is Chloride Channel Activator.

The NADAC file of 2026-10-14 prices it under 11 NDCs (National Drug Codes); the FDA directory lists 9 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $16.96 for 30 capsules (30 × $0.56517 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

The 9 labelers

LabelerNDCsPharmacies pay per unit
American Health Packaging1$0.56517 per EA filed
Camber Pharmaceuticals, Inc.1$0.56517 per EA filed
Dr. Reddy's Laboratories Inc.1$0.56517 per EA filed
Natco Pharma USA LLC1$0.56517 per EA filed
Northstar Rx LLC1$0.56517 per EA filed
Par Health USA, LLC1$0.56517 per EA filed
Sun Pharmaceutical Industries, Inc.1$0.56517 per EA filed
Teva Pharmaceuticals, Inc.1$0.56517 per EA filed
Zydus Pharmaceuticals USA Inc.1$0.56517 per EA filed
Not listed as a package in the FDA directory2$0.56517 per EA filed
All 11 NDCs, with labeler and price
  • 00254-3028-02 · Par Health USA, LLC · $0.56517 per EA · eff. 2026-09-23 filed
  • 00480-3479-06 · Teva Pharmaceuticals, Inc. · $0.56517 per EA · eff. 2026-09-23 filed
  • 31722-0403-60 · Camber Pharmaceuticals, Inc. · $0.56517 per EA · eff. 2026-09-23 filed
  • 43598-0163-60 · Dr. Reddy's Laboratories Inc. · $0.56517 per EA · eff. 2026-09-23 filed
  • 60687-0816-32 · American Health Packaging · $0.56517 per EA · eff. 2026-09-23 filed
  • 60687-0816-33 · not listed as a package in the FDA directory · $0.56517 per EA · eff. 2026-09-23 filed
  • 63304-0351-60 · Sun Pharmaceutical Industries, Inc. · $0.56517 per EA · eff. 2026-09-23 filed
  • 69339-0162-17 · Natco Pharma USA LLC · $0.56517 per EA · eff. 2026-09-23 filed
  • 69339-0162-98 · not listed as a package in the FDA directory · $0.56517 per EA · eff. 2026-09-23 filed
  • 70710-1641-06 · Zydus Pharmaceuticals USA Inc. · $0.56517 per EA · eff. 2026-09-23 filed
  • 72603-0288-01 · Northstar Rx LLC · $0.56517 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

3 other products in the NADAC file share the FDA nonproprietary name lubiprostone with LUBIPROSTONE 8 MCG CAPSULE.

ProductPharmacies pay per unitMedicare per unit
AMITIZA 8 MCG CAPSULE
brand · capsule, gelatin coated
$6.46774 per EA filed
eff. 2026-04-22
$5.65006 per EA filed
Part D 2024 average
AMITIZA 24 MCG CAPSULE
brand · capsule, gelatin coated
$6.44889 per EA filed
eff. 2026-04-22
$5.65006 per EA filed
Part D 2024 average
LUBIPROSTONE 8 MCG CAPSULE this page
generic · capsule, gelatin coated / capsule
$0.56517 per EA filed
eff. 2026-09-23
$1.66781 per EA filed
Part D 2024 average
LUBIPROSTONE 24 MCG CAPSULE
generic · capsule, gelatin coated / capsule
$0.6507 per EA filed
eff. 2026-09-23
$1.66781 per EA filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-04-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 11 NDCs’ NADAC prices is $0.56517 per EA filed.

Of the 3 other products in FDA’s Chloride Channel Activator class priced per EA, 3 have a higher middle NADAC price and 0 a lower one. The one in the middle is AMITIZA 24 MCG CAPSULE, at $6.44889 per EA filed (eff. 2026-04-22).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-04-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $50.03 for 30 capsules, at an average of $1.66781 per EA in 2024 (2024-01-01 to 2024-12-31) for “Lubiprostone”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 440,018 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for LUBIPROSTONE 8 MCG CAPSULE labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Lubiprostone / Lubiprostone: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.