MEMANTINE-DONEPEZIL ER 28-10 MG

What it is

MEMANTINE-DONEPEZIL ER 28-10 MG is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “memantine and donepezil” and “memantine hydrochloride and donepezil hydrochloride”, as its NDCs’ listings variously write the nonproprietary name, under the trade name “Memantine and Donepezil Hydrochlorides Extended-release”.

FDA gives its dosage form as capsule, extended release and its route as oral.

Its labelers, the companies named on the label, are Macleods Pharmaceuticals Limited, Amneal Pharmaceuticals NY LLC and Vitruvias Therapeutics, Inc.

FDA lists it under 2 Established Pharmacologic Classes: Cholinesterase Inhibitor and N-methyl-D-aspartate Receptor Antagonist.

The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $253.34 for 30 capsules (30 × $8.44457 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

What NADAC measures · Why 30 capsules · NADAC explanation codes

All 3 NDCs

• 33342-0313-07 · Macleods Pharmaceuticals Limited · $8.44457 per EA · eff. 2026-09-23 filed
• 69238-1247-03 · Amneal Pharmaceuticals NY LLC · $8.44457 per EA · eff. 2026-09-23 filed
• 69680-0185-30 · Vitruvias Therapeutics, Inc. · $8.44457 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

5 other products in the NADAC file share an FDA nonproprietary name with MEMANTINE-DONEPEZIL ER 28-10 MG.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 3 NDCs’ NADAC prices is $8.44457 per EA filed.

Of the 28 other products in FDA’s Cholinesterase Inhibitor class priced per EA, 6 have a higher middle NADAC price and 22 a lower one. The one in the middle is GALANTAMINE ER 8 MG CAPSULE, at $0.80235 per EA filed (eff. 2026-09-23).

Of the 11 other products in FDA’s N-methyl-D-aspartate Receptor Antagonist class priced per EA, 4 have a higher middle NADAC price and 7 a lower one. The one in the middle is MEMANTINE HCL ER 21 MG CAPSULE, at $0.35626 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

We don’t know yet; the card above says why.

Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.