MESALAMINE 4 GM/60 ML ENEMA
For 1 mL
Pharmacies pay
$0.10 – $0.18 filed
1 × $0.09843 to $0.17585 per ML (the 6 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$5.12 – $5.21 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
MESALAMINE 4 GM/60 ML ENEMA is how the CMS NADAC file names this product. The FDA NDC Directory lists it as mesalamine.
FDA gives its dosage form as “suspension” and “enema” and its route as rectal.
Its labelers, the companies named on the label, are Encube Ethicals, Inc., Padagis Israel Pharmaceuticals Ltd and ANI Pharmaceuticals, Inc.
FDA’s Established Pharmacologic Class for it is Aminosalicylate.
The NADAC file of 2026-10-14 prices it under 6 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $0.10 – $0.18 for 1 mL, depending on the NDC ($0.09843 to $0.17585 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · NADAC explanation codes
All 6 NDCs
- 21922-0045-47 · Encube Ethicals, Inc. · $0.09843 per ML · eff. 2026-09-23 filed
- 21922-0045-49 · Encube Ethicals, Inc. · $0.17585 per ML · eff. 2026-09-23 filed
- 45802-0098-28 · Padagis Israel Pharmaceuticals Ltd · $0.17585 per ML · eff. 2026-09-23 filed
- 45802-0098-51 · Padagis Israel Pharmaceuticals Ltd · $0.09843 per ML · eff. 2026-09-23 filed
- 62559-0420-07 · ANI Pharmaceuticals, Inc. · $0.09843 per ML · eff. 2026-09-23 filed
- 70954-0301-20 · ANI Pharmaceuticals, Inc. · $0.09843 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
10 other products in the NADAC file share the FDA nonproprietary name mesalamine with MESALAMINE 4 GM/60 ML ENEMA.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CANASA 1,000 MG SUPPOSITORY | $37.10967 per EA filed | $36.05608 per EA filed |
| LIALDA DR 1.2 GM TABLET | $8.94652 per EA filed | We don’t know yet |
| MESALAMINE 1,000 MG SUPP | $1.28382 per EA filed | We don’t know yet |
| MESALAMINE 4 GM/60 ML ENEMA this page | $0.09843 to $0.17585 per ML filed | We don’t know yet |
| MESALAMINE 4 GM/60 ML KIT | $134.90444 per EA filed | We don’t know yet |
| MESALAMINE 800 MG DR TABLET | $4.02045 per EA filed | $2.00989 per EA filed |
| MESALAMINE DR 1.2 GM TABLET | $0.7809 per EA filed | $2.00989 per EA filed |
| MESALAMINE DR 400 MG CAPSULE | $2.69898 per EA filed | $2.00989 per EA filed |
| MESALAMINE ER 0.375 GRAM CAP | $0.47798 per EA filed | $1.37992 per EA filed |
| PENTASA 250 MG CAPSULE | $2.90086 per EA filed | $5.03307 per EA filed |
| PENTASA 500 MG CAPSULE | $5.82619 per EA filed | $5.03307 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $0.09843 to $0.17585 per ML for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (420 mL, 1,680 mL). So the card starts at 1 ML; change it to match your prescription.