MESALAMINE ER 0.375 GRAM CAP
For 30 capsules
Pharmacies pay
$14.34 filed
30 × $0.47798 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$41.40 filed
30 × $1.37992 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
2.9× estimated
Medicare paid 2.9× what pharmacies pay.
Part D averages every strength and form sold under “Mesalamine ER” / “Mesalamine” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$21.49 estimated
$14.34 + $2.15 (15%) + $5.00 fee per fill = $21.49
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
MESALAMINE ER 0.375 GRAM CAP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as mesalamine.
FDA gives its dosage form as capsule, extended release and its route as oral.
FDA lists 9 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals USA, Inc., Mylan Pharmaceuticals Inc. and Upsher-Smith Laboratories, LLC.
FDA’s Established Pharmacologic Class for it is Aminosalicylate.
The NADAC file of 2026-10-14 prices it under 11 NDCs (National Drug Codes); the FDA directory lists 9 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $14.34 for 30 capsules (30 × $0.47798 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · Why 30 capsules · NADAC explanation codes
The 9 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Alembic Pharmaceuticals Inc. | 1 | $0.47798 per EA filed |
| American Health Packaging | 1 | $0.47798 per EA filed |
| Ascend Laboratories, LLC | 1 | $0.47798 per EA filed |
| Aurobindo Pharma Limited | 1 | $0.47798 per EA filed |
| AvPAK | 1 | $0.47798 per EA filed |
| Mylan Pharmaceuticals Inc. | 1 | $0.47798 per EA filed |
| Teva Pharmaceuticals USA, Inc. | 1 | $0.47798 per EA filed |
| Upsher-Smith Laboratories, LLC | 1 | $0.47798 per EA filed |
| Zydus Pharmaceuticals USA Inc. | 1 | $0.47798 per EA filed |
| Not listed as a package in the FDA directory | 2 | $0.47798 per EA filed |
All 11 NDCs, with labeler and price
- 00093-9224-89 · Teva Pharmaceuticals USA, Inc. · $0.47798 per EA · eff. 2026-09-23 filed
- 00378-1375-78 · Mylan Pharmaceuticals Inc. · $0.47798 per EA · eff. 2026-09-23 filed
- 00832-6056-12 · Upsher-Smith Laboratories, LLC · $0.47798 per EA · eff. 2026-09-23 filed
- 50268-0577-11 · not listed as a package in the FDA directory · $0.47798 per EA · eff. 2026-09-23 filed
- 50268-0577-15 · AvPAK · $0.47798 per EA · eff. 2026-09-23 filed
- 59651-0397-08 · Aurobindo Pharma Limited · $0.47798 per EA · eff. 2026-09-23 filed
- 60687-0650-32 · American Health Packaging · $0.47798 per EA · eff. 2026-09-23 filed
- 60687-0650-33 · not listed as a package in the FDA directory · $0.47798 per EA · eff. 2026-09-23 filed
- 62332-0724-35 · Alembic Pharmaceuticals Inc. · $0.47798 per EA · eff. 2026-09-23 filed
- 67877-0717-12 · Ascend Laboratories, LLC · $0.47798 per EA · eff. 2026-09-23 filed
- 68382-0452-19 · Zydus Pharmaceuticals USA Inc. · $0.47798 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
10 other products in the NADAC file share the FDA nonproprietary name mesalamine with MESALAMINE ER 0.375 GRAM CAP.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CANASA 1,000 MG SUPPOSITORY | $37.10967 per EA filed | $36.05608 per EA filed |
| LIALDA DR 1.2 GM TABLET | $8.94652 per EA filed | We don’t know yet |
| MESALAMINE 1,000 MG SUPP | $1.28382 per EA filed | We don’t know yet |
| MESALAMINE 4 GM/60 ML ENEMA | $0.09843 to $0.17585 per ML filed | We don’t know yet |
| MESALAMINE 4 GM/60 ML KIT | $134.90444 per EA filed | We don’t know yet |
| MESALAMINE 800 MG DR TABLET | $4.02045 per EA filed | $2.00989 per EA filed |
| MESALAMINE DR 1.2 GM TABLET | $0.7809 per EA filed | $2.00989 per EA filed |
| MESALAMINE DR 400 MG CAPSULE | $2.69898 per EA filed | $2.00989 per EA filed |
| MESALAMINE ER 0.375 GRAM CAP this page | $0.47798 per EA filed | $1.37992 per EA filed |
| PENTASA 250 MG CAPSULE | $2.90086 per EA filed | $5.03307 per EA filed |
| PENTASA 500 MG CAPSULE | $5.82619 per EA filed | $5.03307 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 11 NDCs’ NADAC prices is $0.47798 per EA filed.
Of the 12 other products in FDA’s Aminosalicylate class priced per EA, 9 have a higher middle NADAC price and 3 a lower one. The one in the middle is MESALAMINE DR 400 MG CAPSULE, at $2.69898 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $41.40 for 30 capsules, at an average of $1.37992 per EA in 2024 (2024-01-01 to 2024-12-31) for “Mesalamine ER” and “Mesalamine”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 142,036 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for MESALAMINE ER 0.375 GRAM CAP labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Mesalamine ER / Mesalamine: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.