NASAL DECONGESTANT 0.05% SPRAY
FDA nonproprietary name: oxymetazoline hydrochloride
For 1 mL
Pharmacies pay
$0.08 – $0.12 filed
1 × $0.07516 to $0.12144 per ML (the 4 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$5.09 – $5.14 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
NASAL DECONGESTANT 0.05% SPRAY is how the CMS NADAC file names this product. The FDA NDC Directory lists it as oxymetazoline hydrochloride, under the trade names “Leader Nasal Decongestant” and “Major Nasal Decongestant”.
FDA gives its dosage form as spray and its route as nasal.
Its labelers, the companies named on the label, are Major Pharmaceuticals and Cardinal Health 110,Inc.
FDA’s Established Pharmacologic Class for it is Vasoconstrictor.
The NADAC file of 2026-10-14 prices it under 4 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and marks it as sold over the counter.
What pharmacies pay
Pharmacies pay $0.08 – $0.12 for 1 mL, depending on the NDC ($0.07516 to $0.12144 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
All 4 NDCs
- 00904-7427-30 · Major Pharmaceuticals · $0.07516 per ML · eff. 2026-09-23 filed
- 00904-7435-35 · Major Pharmaceuticals · $0.12144 per ML · eff. 2026-09-23 filed
- 70000-0665-01 · Cardinal Health 110,Inc · $0.09967 per ML · eff. 2026-09-23 filed
- 70000-0676-01 · Cardinal Health 110,Inc · $0.12144 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
8 other products in the NADAC file share the FDA nonproprietary name oxymetazoline hydrochloride with NASAL DECONGESTANT 0.05% SPRAY.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| FT NASAL SPRAY 0.05% | $0.07516 to $0.09967 per ML filed | We don’t know yet |
| GNP NO DRIP NASAL MIST 0.05% | $0.09967 per ML filed | We don’t know yet |
| GS NASAL SPRAY 0.05% | $0.07516 per ML filed | We don’t know yet |
| NASAL DECONGESTANT 0.05% SPRAY this page | $0.07516 to $0.12144 per ML filed | We don’t know yet |
| NASAL SPRAY 0.05% | $0.07516 per ML filed | We don’t know yet |
| NASAL SPRAY ORIGINAL 0.05% | $0.07516 per ML filed | We don’t know yet |
| QC NASAL SPRAY 0.05% | $0.07516 per ML filed | We don’t know yet |
| QC NO DRIP NASAL MIST 0.05% | $0.09967 per ML filed | We don’t know yet |
| RHOFADE 1% CREAM | $23.47434 per GM filed | $19.9853 per GM filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 4 NDCs’ NADAC prices is $0.09967 per ML filed.
Of the 9 other products in FDA’s Vasoconstrictor class priced per ML, 0 have a higher middle NADAC price and 7 a lower one; 2 have the same. The one in the middle is NASAL SPRAY ORIGINAL 0.05%, at $0.07516 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $0.07516 to $0.12144 per ML for this product, depending on the NDC.
- It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (15 mL, 30 mL). So the card starts at 1 ML; change it to match your prescription.