RHOFADE 1% CREAM
FDA nonproprietary name: oxymetazoline hydrochloride
For 30 g
Pharmacies pay
$704.23 filed
30 × $23.47434 per GM
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$599.56 filed
30 × $19.9853 per GM, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.85× estimated
Medicare paid 15% less than pharmacies pay.
Part D averages every strength and form sold under “Rhofade” / “Oxymetazoline HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$814.86 estimated
$704.23 + $105.63 (15%) + $5.00 fee per fill = $814.86
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
RHOFADE 1% CREAM is how the CMS NADAC file names this product. The FDA NDC Directory lists it as oxymetazoline hydrochloride, under the trade name “Rhofade”.
FDA gives its dosage form as cream and its route as topical.
The labeler, the company named on the label, is Mayne Pharma.
FDA’s Established Pharmacologic Class for it is Vasoconstrictor.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 51862-0765-30.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $704.23 for 30 g (30 × $23.47434 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The NDC
- 51862-0765-30 · Mayne Pharma · $23.47434 per GM · eff. 2026-09-23 filed
Other strengths, forms and brands
8 other products in the NADAC file share the FDA nonproprietary name oxymetazoline hydrochloride with RHOFADE 1% CREAM.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| FT NASAL SPRAY 0.05% | $0.07516 to $0.09967 per ML filed | We don’t know yet |
| GNP NO DRIP NASAL MIST 0.05% | $0.09967 per ML filed | We don’t know yet |
| GS NASAL SPRAY 0.05% | $0.07516 per ML filed | We don’t know yet |
| NASAL DECONGESTANT 0.05% SPRAY | $0.07516 to $0.12144 per ML filed | We don’t know yet |
| NASAL SPRAY 0.05% | $0.07516 per ML filed | We don’t know yet |
| NASAL SPRAY ORIGINAL 0.05% | $0.07516 per ML filed | We don’t know yet |
| QC NASAL SPRAY 0.05% | $0.07516 per ML filed | We don’t know yet |
| QC NO DRIP NASAL MIST 0.05% | $0.09967 per ML filed | We don’t know yet |
| RHOFADE 1% CREAM this page | $23.47434 per GM filed | $19.9853 per GM filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
Medicare Part D paid $599.56 for 30 g, at an average of $19.9853 per GM in 2024 (2024-01-01 to 2024-12-31) for “Rhofade” and “Oxymetazoline HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 1,474 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 g? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 30 g; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for RHOFADE 1% CREAM labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Rhofade / Oxymetazoline HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on brand name.
- Why does this page start at 30 g?
- NADAC prices this product per GM. The FDA NDC Directory’s package description gives 30 g in one package for this product’s NDC (“1 TUBE in 1 CARTON (51862-765-30) / 30 g in 1 TUBE”), so the card starts at one package: 30 GM. Change it to match your prescription.