PREDNISOLONE AC 1% EYE DROP
For 1 mL
Pharmacies pay
$4.46 – $4.83 filed
1 × $4.45565 to $4.82733 per ML (the 12 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$5.46 filed
1 × $5.46176 per ML, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.1× – 1.2× estimated
Medicare paid between 1.1× and 1.2× what pharmacies pay, depending on the NDC.
Part D averages every strength and form sold under “Prednisolone Acetate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$10.13 – $10.55 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
PREDNISOLONE AC 1% EYE DROP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as prednisolone acetate.
FDA gives its dosage form as suspension/ drops and its route as ophthalmic.
FDA lists 4 labelers (the companies named on the label) for its NDCs, among them Amneal Pharmaceuticals NY LLC, Pacific Pharma, Inc. and Sandoz Inc.
FDA’s Established Pharmacologic Class for it is Corticosteroid.
The NADAC file of 2026-10-14 prices it under 12 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $4.46 – $4.83 for 1 mL, depending on the NDC ($4.45565 to $4.82733 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · NADAC explanation codes
The 4 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Amneal Pharmaceuticals NY LLC | 3 | $4.45565 to $4.82733 per ML filed |
| Lupin Pharmaceuticals, Inc. | 3 | $4.45565 to $4.82733 per ML filed |
| Pacific Pharma, Inc. | 3 | $4.45565 to $4.82733 per ML filed |
| Sandoz Inc | 3 | $4.45565 to $4.82733 per ML filed |
All 12 NDCs, with labeler and price
- 60219-2550-01 · Amneal Pharmaceuticals NY LLC · $4.82733 per ML · eff. 2026-09-23 filed
- 60219-2551-01 · Amneal Pharmaceuticals NY LLC · $4.72213 per ML · eff. 2026-09-23 filed
- 60219-2552-01 · Amneal Pharmaceuticals NY LLC · $4.45565 per ML · eff. 2026-09-23 filed
- 60758-0119-05 · Pacific Pharma, Inc. · $4.82733 per ML · eff. 2026-09-23 filed
- 60758-0119-10 · Pacific Pharma, Inc. · $4.72213 per ML · eff. 2026-09-23 filed
- 60758-0119-15 · Pacific Pharma, Inc. · $4.45565 per ML · eff. 2026-09-23 filed
- 61314-0637-05 · Sandoz Inc · $4.82733 per ML · eff. 2026-09-23 filed
- 61314-0637-10 · Sandoz Inc · $4.72213 per ML · eff. 2026-09-23 filed
- 61314-0637-15 · Sandoz Inc · $4.45565 per ML · eff. 2026-09-23 filed
- 70748-0332-02 · Lupin Pharmaceuticals, Inc. · $4.82733 per ML · eff. 2026-09-23 filed
- 70748-0332-03 · Lupin Pharmaceuticals, Inc. · $4.72213 per ML · eff. 2026-09-23 filed
- 70748-0332-04 · Lupin Pharmaceuticals, Inc. · $4.45565 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
2 other products in the NADAC file share the FDA nonproprietary name prednisolone acetate with PREDNISOLONE AC 1% EYE DROP.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| PRED FORTE 1% EYE DROPS | $30.7132 to $30.83057 per ML filed | $29.17161 per ML filed |
| PRED MILD 0.12% EYE DROPS | $30.64983 to $30.67471 per ML filed | $32.09796 per ML filed |
| PREDNISOLONE AC 1% EYE DROP this page | $4.45565 to $4.82733 per ML filed | $5.46176 per ML filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-12-17, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 12 NDCs’ NADAC prices is $4.72213 per ML filed.
Of the 106 other products in FDA’s Corticosteroid class priced per ML, 41 have a higher middle NADAC price and 65 a lower one. The one in the middle is FLUNISOLIDE 0.025% SPRAY, at $1.98777 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $5.46 for 1 mL, at an average of $5.46176 per ML in 2024 (2024-01-01 to 2024-12-31) for “Prednisolone Acetate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 3,835,608 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $4.45565 to $4.82733 per ML for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for PREDNISOLONE AC 1% EYE DROP labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Prednisolone Acetate / Prednisolone Acetate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on generic name.
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (5 mL, 10 mL, 15 mL). So the card starts at 1 ML; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- PREDNISONE 1 MG TABLET
- TRELEGY ELLIPTA 100-62.5-25
- METHYLPREDNISOLONE 16 MG TAB
- BREO ELLIPTA 100-25 MCG INHALR
- FLUTICASONE-SALMETEROL 100-50