OpenBilldrug price receipt

NADAC week of 2026-10-14

TRELEGY ELLIPTA 100-62.5-25

FDA nonproprietary name: fluticasone furoate, umeclidinium bromide and vilanterol trifenatate

For 1 unit (EA)

Pharmacies pay

$11.08 – $11.15 filed

1 × $11.07954 to $11.15225 per EA (the 2 NDCs differ)

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$10.52 filed

1 × $10.51883 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

0.94× – 0.95× estimated

Medicare paid between 0.94× and 0.95× what pharmacies pay, depending on the NDC.

Part D averages every strength and form sold under “Trelegy Ellipta” / “Fluticasone/Umeclidin/Vilanter” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$17.74 – $17.82 estimated

NADAC for the pack + 15% + $5.00 fee per fill

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

TRELEGY ELLIPTA 100-62.5-25 is how the CMS NADAC file names this product. The FDA NDC Directory lists it as fluticasone furoate, umeclidinium bromide and vilanterol trifenatate, under the trade name “Trelegy Ellipta”.

FDA gives its dosage form as powder and its route as respiratory (inhalation).

The labeler, the company named on the label, is GlaxoSmithKline LLC.

FDA lists it under 3 Established Pharmacologic Classes: Anticholinergic, beta2-Adrenergic Agonist and Corticosteroid.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $11.08 – $11.15 for 1 unit (EA), depending on the NDC ($11.07954 to $11.15225 per EA), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

All 2 NDCs

Other strengths, forms and brands

1 other product in the NADAC file shares the FDA nonproprietary name fluticasone furoate, umeclidinium bromide and vilanterol trifenatate with TRELEGY ELLIPTA 100-62.5-25.

ProductPharmacies pay per unitMedicare per unit
TRELEGY ELLIPTA 100-62.5-25 this page
brand · powder
$11.07954 to $11.15225 per EA filed
eff. 2026-09-23
$10.51883 per EA filed
Part D 2024 average
TRELEGY ELLIPTA 200-62.5-25
brand · powder
$11.15252 to $11.1997 per EA filed
eff. 2026-09-23
$10.51883 per EA filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $11.07954 per EA filed.

Of the 23 other products in FDA’s Anticholinergic class priced per EA, 3 have a higher middle NADAC price and 20 a lower one. The one in the middle is LOMOTIL 2.5-0.025 MG TABLET, at $2.99096 per EA filed (eff. 2026-09-23).

Of the 26 other products in FDA’s beta2-Adrenergic Agonist class priced per EA, 5 have a higher middle NADAC price and 21 a lower one. The one in the middle is FLUTICASONE-VILANTEROL 200-25, at $3.91371 per EA filed (eff. 2026-09-23).

Of the 73 other products in FDA’s Corticosteroid class priced per EA, 16 have a higher middle NADAC price and 57 a lower one. The one in the middle is FLUTICASONE PROP 100 MCG DISKUS, at $2.05252 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $10.52 for 1 unit (EA), at an average of $10.51883 per EA in 2024 (2024-01-01 to 2024-12-31) for “Trelegy Ellipta” and “Fluticasone/Umeclidin/Vilanter”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 6,250,872 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for TRELEGY ELLIPTA 100-62.5-25 labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Trelegy Ellipta / Fluticasone/Umeclidin/Vilanter: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
Why does this page start at 1 unit (EA)?
NADAC prices this product per EA, and the FDA NDC Directory lists its 2 NDCs as dosage form “POWDER” with route “RESPIRATORY (INHALATION)”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.