PROCHLORPERAZINE 25 MG SUPP
For 1 suppository
Pharmacies pay
$4.87 filed
1 × $4.86511 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$6.91 filed
1 × $6.91173 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.4× estimated
Medicare paid 1.4× what pharmacies pay.
Part D averages every strength and form sold under “Prochlorperazine” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$10.60 estimated
$4.87 + $0.73 (15%) + $5.00 fee per fill = $10.60
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
PROCHLORPERAZINE 25 MG SUPP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as prochlorperazine.
FDA gives its dosage form as suppository and its route as rectal.
The labeler, the company named on the label, is Cosette Pharmaceuticals, Inc.
FDA’s Established Pharmacologic Class for it is Phenothiazine.
The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes); the FDA directory lists 2 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $4.87 for 1 suppository (1 × $4.86511 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · NADAC explanation codes
All 3 NDCs
- 00713-0135-06 · not listed as a package in the FDA directory · $4.86511 per EA · eff. 2026-09-23 filed
- 00713-0135-10 · Cosette Pharmaceuticals, Inc. · $4.86511 per EA · eff. 2026-09-23 filed
- 00713-0135-12 · Cosette Pharmaceuticals, Inc. · $4.86511 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
1 other product in the NADAC file shares the FDA nonproprietary name prochlorperazine with PROCHLORPERAZINE 25 MG SUPP.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| COMPRO 25 MG SUPPOSITORY | $6.74227 per EA filed | $6.58366 per EA filed |
| PROCHLORPERAZINE 25 MG SUPP this page | $4.86511 per EA filed | $6.91173 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 3 NDCs’ NADAC prices is $4.86511 per EA filed.
Of the 32 other products in FDA’s Phenothiazine class priced per EA, 2 have a higher middle NADAC price and 30 a lower one. The one in the middle is CHLORPROMAZINE 50 MG TABLET, at $0.41446 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $6.91 for 1 suppository, at an average of $6.91173 per EA in 2024 (2024-01-01 to 2024-12-31) for “Prochlorperazine”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 3,672 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 suppository? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for PROCHLORPERAZINE 25 MG SUPP labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Prochlorperazine / Prochlorperazine: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
- Why does this page start at 1 suppository?
- NADAC prices this product per EA, and the FDA NDC Directory lists 2 of its 3 NDCs (it does not list the other one) as dosage form “SUPPOSITORY” with route “RECTAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. So the card starts at 1 suppository, priced per suppository, rather than guess how many make up a fill; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- CHLORPROMAZINE 10 MG TABLET
- FLUPHENAZINE 1 MG TABLET
- PERPHENAZINE 16 MG TABLET
- FLUPHENAZINE DEC 125 MG/5 ML
- TRIFLUOPERAZINE 1 MG TABLET