PROPAFENONE HCL ER 225 MG CAP

What it is

PROPAFENONE HCL ER 225 MG CAP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “propafenone hydrochloride” and “propafenone”, as its NDCs’ listings variously write the nonproprietary name.

FDA gives its dosage form as capsule, extended release and its route as oral.

FDA lists 6 labelers (the companies named on the label) for its NDCs, among them Upsher-Smith Laboratories, LLC, Rising Pharma Holdings, Inc. and Northstar Rx LLC.

FDA’s Established Pharmacologic Class for it is Antiarrhythmic.

The NADAC file of 2026-10-14 prices it under 10 NDCs (National Drug Codes); the FDA directory lists 6 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $8.98 for 30 capsules (30 × $0.29932 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

What NADAC measures · Why 30 capsules · NADAC explanation codes

The 6 labelers

Other strengths, forms and brands

5 other products in the NADAC file share an FDA nonproprietary name with PROPAFENONE HCL ER 225 MG CAP.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 10 NDCs’ NADAC prices is $0.29932 per EA filed.

Of the 43 other products in FDA’s Antiarrhythmic class priced per EA, 24 have a higher middle NADAC price and 19 a lower one. The one in the middle is PROPAFENONE HCL 300 MG TAB, at $0.38802 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $49.57 for 30 capsules, at an average of $1.65246 per EA in 2024 (2024-01-01 to 2024-12-31) for “Propafenone HCl ER” and “Propafenone HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 68,242 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.