Why does this page start at 473 mL?

NADAC prices this product per ML. The FDA NDC Directory’s package description gives 473 mL in one package for all 5 NDCs of this product (“473 mL in 1 BOTTLE, PLASTIC (16571-833-16)”), so the card starts at one package: 473 ML. Change it to match your prescription.

PYRIDOSTIGMINE 60 MG/5 ML SOLN

For 473 mL

Pharmacies pay

$267.17 filed

473 × $0.56484 per ML

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare

We don’t know yet

No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.

The spread

We don’t know yet

There is no Medicare figure to compare with, so there is no spread.

Cost-plus estimate

$312.25 estimated

$267.17 + $40.08 (15%) + $5.00 fee per fill = $312.25

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

PYRIDOSTIGMINE 60 MG/5 ML SOLN is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “pyridostigmine bromide” and “pyridostigmine bromide oral”, as its NDCs’ listings variously write the nonproprietary name, under the trade names “Pryidostigmine Bromide” and “Pyridostigmine”.

FDA gives its dosage form as solution and its route as oral.

FDA lists 5 labelers (the companies named on the label) for its NDCs, among them Rising Pharma Holdings, Inc., Acella Pharmaceuticals, LLC and Amneal Pharmaceuticals NY LLC.

FDA’s Established Pharmacologic Class for it is Cholinesterase Inhibitor.

The NADAC file of 2026-10-14 prices it under 5 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $267.17 for 473 mL (473 × $0.56484 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

What NADAC measures · NADAC explanation codes

All 5 NDCs

16571-0833-16 · Rising Pharma Holdings, Inc. · $0.56484 per ML · eff. 2026-09-23 filed
42192-0626-16 · Acella Pharmaceuticals, LLC · $0.56484 per ML · eff. 2026-09-23 filed
69238-1731-02 · Amneal Pharmaceuticals NY LLC · $0.56484 per ML · eff. 2026-09-23 filed
70954-0148-10 · Novitium Pharma LLC · $0.56484 per ML · eff. 2026-09-23 filed
72205-0098-72 · Novadoz Pharmaceuticals LLC · $0.56484 per ML · eff. 2026-09-23 filed

Other strengths, forms and brands

3 other products in the NADAC file share an FDA nonproprietary name with PYRIDOSTIGMINE 60 MG/5 ML SOLN.

Product	Pharmacies pay per unit	Medicare per unit
PYRIDOSTIGMINE 60 MG/5 ML SOLN this page generic · solution	$0.56484 per ML filed eff. 2026-09-23	We don’t know yet
PYRIDOSTIGMINE BR 30 MG TABLET generic · tablet	$6.94704 per EA filed eff. 2026-09-23	We don’t know yet
PYRIDOSTIGMINE BR 60 MG TABLET generic · tablet	$0.24872 per EA filed eff. 2026-09-23	We don’t know yet
PYRIDOSTIGMINE ER 180 MG TAB generic · tablet, extended release / tablet	$3.99632 per EA filed eff. 2026-09-23	$6.69477 per EA filed Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

What Medicare paid

We don’t know yet; the card above says why.

Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

What is your cash price for 473 mL? Is it lower than what I would pay through my insurance?
How much is in the package I am getting? This page uses 473 mL; your package may hold a different amount.
These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.

Questions

Why does this page start at 473 mL?: NADAC prices this product per ML. The FDA NDC Directory’s package description gives 473 mL in one package for all 5 NDCs of this product (“473 mL in 1 BOTTLE, PLASTIC (16571-833-16)”), so the card starts at one package: 473 ML. Change it to match your prescription.

Its pharmacologic class

Cholinesterase Inhibitor 31 products