REFRESH OPTIVE EYE DROPS
FDA nonproprietary name: carboxymethylcellulose sodium and glycerin
For 15 mL
Pharmacies pay
$9.89 filed
15 × $0.65911 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$16.37 estimated
$9.89 + $1.48 (15%) + $5.00 fee per fill = $16.37
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-08-19 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
REFRESH OPTIVE EYE DROPS is how the CMS NADAC file names this product. The FDA NDC Directory lists it as carboxymethylcellulose sodium and glycerin, under the trade name “REFRESH OPTIVE”.
FDA gives its dosage form as solution/ drops and its route as ophthalmic.
The labeler, the company named on the label, is Allergan, Inc.
FDA’s Established Pharmacologic Class for it is Non-Standardized Chemical Allergen.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00023-3240-15.
NADAC classes it as a brand-name drug (rate-setting class B), and marks it as sold over the counter.
What pharmacies pay
Pharmacies pay $9.89 for 15 mL (15 × $0.65911 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-08-19. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-08-19. The file is new; the price is not.
What NADAC measures · NADAC explanation codes · Carried-forward prices
The NDC
- 00023-3240-15 · Allergan, Inc. · $0.65911 per ML · eff. 2026-08-19 filed carried forward
Other strengths, forms and brands
4 other products in the NADAC file share the FDA nonproprietary name carboxymethylcellulose sodium and glycerin with REFRESH OPTIVE EYE DROPS.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| REFRESH OPTIVE EYE DROPS this page | $0.65911 per ML filed | We don’t know yet |
| REFRESH OPTIVE GEL EYE DROPS | $1.09895 per ML filed | We don’t know yet |
| REFRESH RELIEVA PF 0.5-0.9% DP | $1.2541 per ML filed | We don’t know yet |
| REFRESH RELIEVA PF 0.5-1% DROP | $0.45293 per EA filed | We don’t know yet |
| REFRESH RELIEVA PF XTRA DROP | $1.2541 per ML filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-05-20, 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Compared with its class
Its NADAC price is $0.65911 per ML filed.
Of the 12 other products in FDA’s Non-Standardized Chemical Allergen class priced per ML, 6 have a higher middle NADAC price and 6 a lower one. The one in the middle is GENTEAL TEARS 0.1%-0.2%-0.3%, at $0.42498 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 15 mL? Is it lower than what I would pay through my insurance?
- It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
- How much is in the package I am getting? This page uses 15 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 15 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 15 mL in one package for this product’s NDC (“1 BOTTLE, DROPPER in 1 CARTON (0023-3240-15) / 15 mL in 1 BOTTLE, DROPPER”), so the card starts at one package: 15 ML. Change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- ARTIFICIAL TEARS 0.1-0.2-0.3%
- CHILD GLYCERIN 1.2 GM SUPP
- DRY EYE RELIEF EYE DROPS
- GENTEAL TEARS 0.1%-0.2%-0.3%
- GNP HEMORRHOIDAL PAIN RLF CRM