Why does this page start at 1 unit (EA)?

NADAC prices this product per EA, and the FDA NDC Directory lists its NDC as dosage form “SOLUTION/ DROPS” with route “OPHTHALMIC”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.

REFRESH RELIEVA PF 0.5-1% DROP

FDA nonproprietary name: carboxymethylcellulose sodium and glycerin

For 1 unit (EA)

Pharmacies pay

$0.45 filed

1 × $0.45293 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-05-20 · as of 2026-10-14 · retrieved 2026-10-17

Medicare

We don’t know yet

No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.

The spread

We don’t know yet

There is no Medicare figure to compare with, so there is no spread.

Cost-plus estimate

$5.52 estimated

$0.45 + $0.07 (15%) + $5.00 fee per fill = $5.52

This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-05-20 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

REFRESH RELIEVA PF 0.5-1% DROP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as carboxymethylcellulose sodium and glycerin, under the trade name “Refresh RELIEVA PF”.

FDA gives its dosage form as solution/ drops and its route as ophthalmic.

The labeler, the company named on the label, is Allergan, Inc.

FDA’s Established Pharmacologic Class for it is Non-Standardized Chemical Allergen.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00023-4515-30.

NADAC classes it as a brand-name drug (rate-setting class B), and marks it as sold over the counter.

What pharmacies pay

Pharmacies pay $0.45 for 1 unit (EA) (1 × $0.45293 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-05-20. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-05-20. The file is new; the price is not.

What NADAC measures · NADAC explanation codes · Carried-forward prices

The NDC

00023-4515-30 · Allergan, Inc. · $0.45293 per EA · eff. 2026-05-20 filed carried forward

Other strengths, forms and brands

4 other products in the NADAC file share the FDA nonproprietary name carboxymethylcellulose sodium and glycerin with REFRESH RELIEVA PF 0.5-1% DROP.

Product	Pharmacies pay per unit	Medicare per unit
REFRESH OPTIVE EYE DROPS brand · solution/ drops	$0.65911 per ML filed eff. 2026-08-19	We don’t know yet
REFRESH OPTIVE GEL EYE DROPS brand · solution/ drops	$1.09895 per ML filed eff. 2026-08-19	We don’t know yet
REFRESH RELIEVA PF 0.5-0.9% DP brand · solution/ drops	$1.2541 per ML filed eff. 2026-09-23	We don’t know yet
REFRESH RELIEVA PF 0.5-1% DROP this page brand · solution/ drops	$0.45293 per EA filed eff. 2026-05-20	We don’t know yet
REFRESH RELIEVA PF XTRA DROP brand · solution/ drops	$1.2541 per ML filed eff. 2026-09-23	We don’t know yet

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-05-20, 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Compared with its class

Its NADAC price is $0.45293 per EA filed.

Of the 10 other products in FDA’s Non-Standardized Chemical Allergen class priced per EA, 0 have a higher middle NADAC price and 10 a lower one. The one in the middle is CHILD GLYCERIN SUPPOSITORY, at $0.12192 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-05-20, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

We don’t know yet; the card above says why.

Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.

Questions

Why does this page start at 1 unit (EA)?: NADAC prices this product per EA, and the FDA NDC Directory lists its NDC as dosage form “SOLUTION/ DROPS” with route “OPHTHALMIC”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.

Its pharmacologic class

Non-Standardized Chemical Allergen 28 products