Why is the comparison with Medicare for TIMOLOL 0.5% GFS GEL-SOLUTION labelled estimated?

Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Timolol Maleate* / Timolol Maleate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes OPHTHALMIC point at this name (10 of the 12 the name join matched); NDCs of another route or with no known FDA route do not.

Why does this page start at 5 mL?

NADAC prices this product per ML. The FDA NDC Directory’s package description gives 5 mL in one package for this product’s NDC (“5 mL in 1 BOTTLE (61314-225-05)”), so the card starts at one package: 5 ML. Change it to match your prescription.

TIMOLOL 0.5% GFS GEL-SOLUTION

For 5 mL

Pharmacies pay

$41.51 filed

5 × $8.30197 per ML

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$10.05 filed

5 × $2.00991 per ML, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

The spread

0.24× estimated

Medicare paid 76% less than pharmacies pay.

Part D averages every strength and form sold under “Timolol Maleate*” / “Timolol Maleate” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$52.74 estimated

$41.51 + $6.23 (15%) + $5.00 fee per fill = $52.74

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

TIMOLOL 0.5% GFS GEL-SOLUTION is how the CMS NADAC file names this product. The FDA NDC Directory lists it as timolol maleate, under the trade name “Timolol GFS”.

FDA gives its dosage form as solution, gel forming / drops and its route as ophthalmic.

The labeler, the company named on the label, is Sandoz Inc.

FDA’s Established Pharmacologic Class for it is beta-Adrenergic Blocker.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 61314-0225-05.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $41.51 for 5 mL (5 × $8.30197 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

What NADAC measures · NADAC explanation codes

The NDC

61314-0225-05 · Sandoz Inc · $8.30197 per ML · eff. 2026-09-23 filed

Other strengths, forms and brands

8 other products in the NADAC file share the FDA nonproprietary name timolol maleate with TIMOLOL 0.5% GFS GEL-SOLUTION.

Product	Pharmacies pay per unit	Medicare per unit
ISTALOL 0.5% EYE DROPS brand · solution/ drops	$79.76333 to $80.01457 per ML filed eff. 2026-06-17 to 2026-07-22	$78.53935 per ML filed Part D 2024 average
TIMOLOL 0.25% GEL-SOLUTION generic · solution, gel forming / drops / solution/ drops / solution	$6.37609 per ML filed eff. 2026-09-23	$2.00991 per ML filed Part D 2024 average
TIMOLOL 0.5% EYE DROP generic · solution/ drops	$21.80573 to $22.28973 per ML filed eff. 2026-09-23	We don’t know yet
TIMOLOL 0.5% GEL-SOLUTION generic · solution, gel forming / drops / solution/ drops / solution	$8.30197 per ML filed eff. 2026-09-23	$2.00991 per ML filed Part D 2024 average
TIMOLOL 0.5% GFS GEL-SOLUTION this page generic · solution, gel forming / drops	$8.30197 per ML filed eff. 2026-09-23	$2.00991 per ML filed Part D 2024 average
TIMOLOL MALEATE 0.25% EYE DROP generic · solution/ drops / solution	$0.60023 to $0.64657 per ML; $6.10159 per EA filed eff. 2026-09-23	We don’t know yet
TIMOLOL MALEATE 0.5% EYE DROP generic · solution/ drops / solution	$1.25546 per EA filed eff. 2026-09-23	We don’t know yet
TIMOLOL MALEATE 0.5% EYE DROPS generic · solution/ drops / solution	$0.71967 to $1.046 per ML filed eff. 2026-09-23	We don’t know yet
TIMOPTIC 0.5% OCUDOSE DROP brand · solution	$10.32362 per EA filed eff. 2026-09-23	We don’t know yet

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-06-17, 2026-07-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

Its NADAC price is $8.30197 per ML filed.

Of the 19 other products in FDA’s beta-Adrenergic Blocker class priced per ML, 8 have a higher middle NADAC price and 10 a lower one; 1 has the same. The one in the middle is TIMOLOL 0.25% GEL-SOLUTION, at $6.37609 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $10.05 for 5 mL, at an average of $2.00991 per ML in 2024 (2024-01-01 to 2024-12-31) for “Timolol Maleate*” and “Timolol Maleate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 2,958,063 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

What is your cash price for 5 mL? Is it lower than what I would pay through my insurance?
How much is in the package I am getting? This page uses 5 mL; your package may hold a different amount.
If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.

Questions

Why is the comparison with Medicare for TIMOLOL 0.5% GFS GEL-SOLUTION labelled estimated?: Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Timolol Maleate* / Timolol Maleate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes OPHTHALMIC point at this name (10 of the 12 the name join matched); NDCs of another route or with no known FDA route do not.
Why does this page start at 5 mL?: NADAC prices this product per ML. The FDA NDC Directory’s package description gives 5 mL in one package for this product’s NDC (“5 mL in 1 BOTTLE (61314-225-05)”), so the card starts at one package: 5 ML. Change it to match your prescription.

Its pharmacologic class

beta-Adrenergic Blocker 98 products