OpenBilldrug price receipt

NADAC week of 2026-10-14

TRETINOIN 0.1% CREAM

For 1 g

Pharmacies pay

$0.77 – $0.92 filed

1 × $0.77008 to $0.91963 per GM (the 14 NDCs differ)

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$1.97 filed

1 × $1.97 per GM, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

2.1× – 2.6× estimated

Medicare paid between 2.1× and 2.6× what pharmacies pay, depending on the NDC.

Part D averages every strength and form sold under “Tretinoin*” / “Tretinoin” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$5.89 – $6.06 estimated

NADAC for the pack + 15% + $5.00 fee per fill

This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

TRETINOIN 0.1% CREAM is how the CMS NADAC file names this product. The FDA NDC Directory lists it as tretinoin.

FDA gives its dosage form as cream and its route as topical.

FDA lists 7 labelers (the companies named on the label) for its NDCs, among them Mylan Pharmaceuticals Inc., Padagis US LLC and NORTHSTAR RX LLC.

FDA’s Established Pharmacologic Class for it is Retinoid.

The NADAC file of 2026-10-14 prices it under 14 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $0.77 – $0.92 for 1 g, depending on the NDC ($0.77008 to $0.91963 per GM), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

The 7 labelers

LabelerNDCsPharmacies pay per unit
Alembic Pharmaceuticals Inc.2$0.77008 to $0.91963 per GM filed
Encube Ethicals, Inc.2$0.77008 to $0.91963 per GM filed
Mylan Pharmaceuticals Inc.2$0.77008 to $0.91963 per GM filed
NORTHSTAR RX LLC2$0.77008 to $0.91963 per GM filed
Padagis US LLC2$0.77008 to $0.91963 per GM filed
Sun Pharmaceutical Industries, Inc.2$0.77008 to $0.91963 per GM filed
Viona Pharmaceuticals Inc2$0.77008 to $0.91963 per GM filed
All 14 NDCs, with labeler and price
  • 00378-8084-20 · Mylan Pharmaceuticals Inc. · $0.91963 per GM · eff. 2026-09-23 filed
  • 00378-8084-45 · Mylan Pharmaceuticals Inc. · $0.77008 per GM · eff. 2026-09-23 filed
  • 00574-2201-20 · Padagis US LLC · $0.91963 per GM · eff. 2026-09-23 filed
  • 00574-2201-45 · Padagis US LLC · $0.77008 per GM · eff. 2026-09-23 filed
  • 16714-0250-01 · NORTHSTAR RX LLC · $0.91963 per GM · eff. 2026-09-23 filed
  • 16714-0250-02 · NORTHSTAR RX LLC · $0.77008 per GM · eff. 2026-09-23 filed
  • 21922-0077-06 · Encube Ethicals, Inc. · $0.77008 per GM · eff. 2026-09-23 filed
  • 21922-0077-25 · Encube Ethicals, Inc. · $0.91963 per GM · eff. 2026-09-23 filed
  • 51672-1395-00 · Sun Pharmaceutical Industries, Inc. · $0.91963 per GM · eff. 2026-09-23 filed
  • 51672-1395-09 · Sun Pharmaceutical Industries, Inc. · $0.77008 per GM · eff. 2026-09-23 filed
  • 62332-0807-20 · Alembic Pharmaceuticals Inc. · $0.91963 per GM · eff. 2026-09-23 filed
  • 62332-0807-45 · Alembic Pharmaceuticals Inc. · $0.77008 per GM · eff. 2026-09-23 filed
  • 72578-0153-08 · Viona Pharmaceuticals Inc · $0.77008 per GM · eff. 2026-09-23 filed
  • 72578-0153-09 · Viona Pharmaceuticals Inc · $0.91963 per GM · eff. 2026-09-23 filed

Other strengths, forms and brands

7 other products in the NADAC file share the FDA nonproprietary name tretinoin with TRETINOIN 0.1% CREAM.

ProductPharmacies pay per unitMedicare per unit
TRETINOIN 0.01% GEL
generic · gel
$2.3019 to $2.73988 per GM filed
eff. 2026-09-23
$1.97 per GM filed
Part D 2024 average
TRETINOIN 0.025% CREAM
generic · cream
$0.45929 to $0.55294 per GM filed
eff. 2026-09-23
$1.97 per GM filed
Part D 2024 average
TRETINOIN 0.025% GEL
generic · gel
$2.50019 to $3.54983 per GM filed
eff. 2026-09-23
$1.97 per GM filed
Part D 2024 average
TRETINOIN 0.05% CREAM
generic · cream
$1.05049 to $1.61765 per GM filed
eff. 2026-09-23
$1.97 per GM filed
Part D 2024 average
TRETINOIN 0.05% GEL
generic · gel
$3.93282 per GM filed
eff. 2026-09-23
$1.97 per GM filed
Part D 2024 average
TRETINOIN 0.1% CREAM this page
generic · cream
$0.77008 to $0.91963 per GM filed
eff. 2026-09-23
$1.97 per GM filed
Part D 2024 average
TRETINOIN 10 MG CAPSULE
generic · capsule
$8.53098 per EA filed
eff. 2026-09-23
We don’t know yet
TRETINOIN GEL MICRO 0.08% PUMP
generic · gel
$11.46457 per GM filed
eff. 2026-09-23
We don’t know yet

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 14 NDCs’ NADAC prices is $0.77008 per GM filed.

Of the 23 other products in FDA’s Retinoid class priced per GM, 17 have a higher middle NADAC price and 6 a lower one. The one in the middle is ADAPALENE 0.1% CREAM, at $2.85454 per GM filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $1.97 for 1 g, at an average of $1.97 per GM in 2024 (2024-01-01 to 2024-12-31) for “Tretinoin*” and “Tretinoin”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 235,091 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for TRETINOIN 0.1% CREAM labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Tretinoin* / Tretinoin: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes TOPICAL point at this name (53 of the 58 the name join matched); NDCs of another route or with no known FDA route do not. 53 of 58 NADAC NDCs joined to this name are priced per GM (5 per EA): CMS's average mixes those units.
Why does this page start at 1 g?
The FDA package descriptions of this product’s NDCs give different amounts (20 g, 45 g). So the card starts at 1 GM; change it to match your prescription.