TRIJARDY XR 12.5-2.5-1,000 MG
FDA nonproprietary name: empagliflozin, linagliptin, metformin hydrochloride
For 30 tablets
Pharmacies pay
$168.83 filed
30 × $5.62766 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$424.65 filed
30 × $14.15485 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
2.5× estimated
Medicare paid 2.5× what pharmacies pay.
Part D averages every strength and form sold under “Trijardy XR” / “Empaglifloz/Linaglip/Metformin” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$199.15 estimated
$168.83 + $25.32 (15%) + $5.00 fee per fill = $199.15
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
TRIJARDY XR 12.5-2.5-1,000 MG is how the CMS NADAC file names this product. The FDA NDC Directory lists it as empagliflozin, linagliptin, metformin hydrochloride, under the trade name “Trijardy XR”.
FDA gives its dosage form as tablet, extended release and its route as oral.
The labeler, the company named on the label, is Boehringer Ingelheim Pharmaceuticals, Inc.
FDA lists it under 3 Established Pharmacologic Classes: Biguanide, Dipeptidyl Peptidase 4 Inhibitor and Sodium-Glucose Cotransporter 2 Inhibitor.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $168.83 for 30 tablets (30 × $5.62766 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
All 2 NDCs
- 00597-0385-77 · Boehringer Ingelheim Pharmaceuticals, Inc. · $5.62766 per EA · eff. 2026-09-23 filed
- 00597-0385-86 · Boehringer Ingelheim Pharmaceuticals, Inc. · $5.62766 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
3 other products in the NADAC file share the FDA nonproprietary name empagliflozin, linagliptin, metformin hydrochloride with TRIJARDY XR 12.5-2.5-1,000 MG.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| TRIJARDY XR 5-2.5-1,000 MG TAB | $5.66862 per EA filed | $14.15485 per EA filed |
| TRIJARDY XR 10-5-1,000 MG TAB | $11.2774 per EA filed | $14.15485 per EA filed |
| TRIJARDY XR 12.5-2.5-1,000 MG this page | $5.62766 per EA filed | $14.15485 per EA filed |
| TRIJARDY XR 25-5-1,000 MG TAB | $11.23864 per EA filed | $14.15485 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 2 NDCs’ NADAC prices is $5.62766 per EA filed.
Of the 71 other products in FDA’s Biguanide class priced per EA, 32 have a higher middle NADAC price and 39 a lower one. The one in the middle is SYNJARDY 12.5-1,000 MG TABLET, at $5.60127 per EA filed (eff. 2026-09-23).
Of the 43 other products in FDA’s Dipeptidyl Peptidase 4 Inhibitor class priced per EA, 21 have a higher middle NADAC price and 22 a lower one. The one in the middle is JANUMET 50-500 MG TABLET, at $5.28403 per EA filed (eff. 2026-09-23).
Of the 39 other products in FDA’s Sodium-Glucose Cotransporter 2 Inhibitor class priced per EA, 27 have a higher middle NADAC price and 12 a lower one. The one in the middle is XIGDUO XR 2.5 MG-1,000 MG TAB, at $9.60825 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $424.65 for 30 tablets, at an average of $14.15485 per EA in 2024 (2024-01-01 to 2024-12-31) for “Trijardy XR” and “Empaglifloz/Linaglip/Metformin”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 112,533 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for TRIJARDY XR 12.5-2.5-1,000 MG labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Trijardy XR / Empaglifloz/Linaglip/Metformin: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
Related pages
Its pharmacologic classes
Related in the same class
- JANUMET 50-1,000 MG TABLET
- SYNJARDY XR 10-1,000 MG TABLET
- SYNJARDY 12.5-1,000 MG TABLET
- GLYXAMBI 10 MG-5 MG TABLET
- JENTADUETO 2.5 MG-1,000 MG TAB