XIGDUO XR 10 MG-1,000 MG TAB
FDA nonproprietary name: dapagliflozin and metformin hydrochloride
For 30 tablets
Pharmacies pay
$576.13 filed
30 × $19.20443 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$408.22 filed
30 × $13.6073 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.71× estimated
Medicare paid 29% less than pharmacies pay.
Part D averages every strength and form sold under “Xigduo XR” / “Dapaglifloz Propaned/Metformin” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$667.55 estimated
$576.13 + $86.42 (15%) + $5.00 fee per fill = $667.55
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
XIGDUO XR 10 MG-1,000 MG TAB is how the CMS NADAC file names this product. The FDA NDC Directory lists it as dapagliflozin and metformin hydrochloride, under the trade name “XIGDUO XR”.
FDA gives its dosage form as tablet, film coated, extended release and its route as oral.
The labeler, the company named on the label, is AstraZeneca Pharmaceuticals LP.
FDA lists it under 2 Established Pharmacologic Classes: Biguanide and Sodium-Glucose Cotransporter 2 Inhibitor.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00310-6280-30.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $576.13 for 30 tablets (30 × $19.20443 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $0.71952 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · Why 30 tablets · NADAC explanation codes
The NDC
- 00310-6280-30 · AstraZeneca Pharmaceuticals LP · $19.20443 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
8 other products in the NADAC file share the FDA nonproprietary name dapagliflozin and metformin hydrochloride with XIGDUO XR 10 MG-1,000 MG TAB.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| DAPAGLIFLOZIN-METFORMIN ER 5-1,000 MG TABLET | $0.46063 per EA filed | $10.47878 per EA filed |
| DAPAGLIFLOZIN-METFORMIN ER 5-500 MG TABLET | $0.70725 per EA filed | $10.47878 per EA filed |
| DAPAGLIFLOZIN-METFORMIN ER 10-1,000 MG TABLET | $0.71952 per EA filed | $10.47878 per EA filed |
| DAPAGLIFLOZIN-METFORMIN ER 10-500 MG TABLET | $0.80198 per EA filed | $10.47878 per EA filed |
| XIGDUO XR 2.5 MG-1,000 MG TAB | $9.60825 per EA filed | $13.6073 per EA filed |
| XIGDUO XR 5 MG-1,000 MG TABLET | $9.59236 per EA filed | $13.6073 per EA filed |
| XIGDUO XR 5 MG-500 MG TABLET | $19.18159 per EA filed | $13.6073 per EA filed |
| XIGDUO XR 10 MG-1,000 MG TAB this page | $19.20443 per EA filed | $13.6073 per EA filed |
| XIGDUO XR 10 MG-500 MG TABLET | $19.2391 per EA filed | $13.6073 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $19.20443 per EA filed.
Of the 71 other products in FDA’s Biguanide class priced per EA, 1 has a higher middle NADAC price and 70 a lower one. The one in the middle is SYNJARDY 12.5-1,000 MG TABLET, at $5.60127 per EA filed (eff. 2026-09-23).
Of the 39 other products in FDA’s Sodium-Glucose Cotransporter 2 Inhibitor class priced per EA, 2 have a higher middle NADAC price and 37 a lower one. The one in the middle is XIGDUO XR 5 MG-1,000 MG TABLET, at $9.59236 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $408.22 for 30 tablets, at an average of $13.6073 per EA in 2024 (2024-01-01 to 2024-12-31) for “Xigduo XR” and “Dapaglifloz Propaned/Metformin”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 215,012 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: DAPAGLIFLOZIN-METFORMIN ER 10-1,000 MG TABLET. Ask your pharmacist or prescriber; do not switch on your own.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for XIGDUO XR 10 MG-1,000 MG TAB labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Xigduo XR / Dapaglifloz Propaned/Metformin: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
Related pages
Its pharmacologic classes
Related in the same class
- SYNJARDY XR 10-1,000 MG TABLET
- SYNJARDY 12.5-1,000 MG TABLET
- TRIJARDY XR 10-5-1,000 MG TAB
- INVOKAMET XR 150-1,000 MG TAB
- JARDIANCE 10 MG TABLET