ZUBSOLV 2.9-0.71 MG TABLET SL

What it is

ZUBSOLV 2.9-0.71 MG TABLET SL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as buprenorphine hydrochloride and naloxone hydrochloride, under the trade name “Zubsolv”.

FDA gives its dosage form as tablet, orally disintegrating and its route as sublingual.

Its labelers, the companies named on the label, are Orexo US, Inc. and Edenbridge Pharmaceuticals LLC.

FDA lists it under 2 Established Pharmacologic Classes: Opioid Antagonist and Partial Opioid Agonist.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $315.56 for 30 tablets (30 × $10.51861 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

What NADAC measures · NADAC explanation codes

All 2 NDCs

• 54123-0929-30 · Orexo US, Inc. · $10.51861 per EA · eff. 2026-09-23 filed
• 82111-0203-30 · Edenbridge Pharmaceuticals LLC. · $10.51861 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

7 other products in the NADAC file share the FDA nonproprietary name buprenorphine hydrochloride and naloxone hydrochloride with ZUBSOLV 2.9-0.71 MG TABLET SL.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $10.51861 per EA filed.

Of the 30 other products in FDA’s Opioid Antagonist class priced per EA, 17 have a higher middle NADAC price and 13 a lower one. The one in the middle is MOVANTIK 12.5 MG TABLET, at $14.59872 per EA filed (eff. 2026-09-23).

Of the 34 other products in FDA’s Partial Opioid Agonist class priced per EA, 19 have a higher middle NADAC price and 15 a lower one. The one in the middle is BELBUCA 300 MCG FILM, at $11.85628 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $334.42 for 30 tablets, at an average of $11.14749 per EA in 2024 (2024-01-01 to 2024-12-31) for “Zubsolv” and “Buprenorphine HCl/Naloxone HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 49,425 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.