ACETAZOLAMIDE 250 MG TABLET
For 30 tablets
Pharmacies pay
$4.02 filed
30 × $0.13397 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$18.24 filed
30 × $0.6079 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
4.5× estimated
Medicare paid 4.5× what pharmacies pay.
Part D averages every strength and form sold under “Acetazolamide” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$9.62 estimated
$4.02 + $0.60 (15%) + $5.00 fee per fill = $9.62
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
ACETAZOLAMIDE 250 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as acetazolamide.
FDA gives its dosage form as tablet and its route as oral.
FDA lists 12 labelers (the companies named on the label) for its NDCs, among them Major Pharmaceuticals, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. and AvPAK.
FDA’s Established Pharmacologic Class for it is Carbonic Anhydrase Inhibitor.
The NADAC file of 2026-10-14 prices it under 13 NDCs (National Drug Codes); the FDA directory lists 12 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $4.02 for 30 tablets (30 × $0.13397 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 12 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| ANI Pharmaceuticals, Inc. | 1 | $0.13397 per EA filed |
| Advagen Pharma Ltd | 1 | $0.13397 per EA filed |
| Aurobindo Pharma Limited | 1 | $0.13397 per EA filed |
| AvPAK | 1 | $0.13397 per EA filed |
| Chartwell RX, LLC | 1 | $0.13397 per EA filed |
| Eywa Pharma Inc | 1 | $0.13397 per EA filed |
| Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 1 | $0.13397 per EA filed |
| Lifestar Pharma LLC | 1 | $0.13397 per EA filed |
| Major Pharmaceuticals | 1 | $0.13397 per EA filed |
| Strides Pharma Science Limited | 1 | $0.13397 per EA filed |
| TRUPHARMA, LLC | 1 | $0.13397 per EA filed |
| Viona Pharmaceuticals Inc | 1 | $0.13397 per EA filed |
| Not listed as a package in the FDA directory | 1 | $0.13397 per EA filed |
All 13 NDCs, with labeler and price
- 00904-6663-61 · Major Pharmaceuticals · $0.13397 per EA · eff. 2026-09-23 filed
- 23155-0288-01 · Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. · $0.13397 per EA · eff. 2026-09-23 filed
- 50268-0054-11 · not listed as a package in the FDA directory · $0.13397 per EA · eff. 2026-09-23 filed
- 50268-0054-15 · AvPAK · $0.13397 per EA · eff. 2026-09-23 filed
- 52817-0201-10 · TRUPHARMA, LLC · $0.13397 per EA · eff. 2026-09-23 filed
- 59651-0906-01 · Aurobindo Pharma Limited · $0.13397 per EA · eff. 2026-09-23 filed
- 62135-0608-12 · Chartwell RX, LLC · $0.13397 per EA · eff. 2026-09-23 filed
- 64380-0834-06 · Strides Pharma Science Limited · $0.13397 per EA · eff. 2026-09-23 filed
- 70756-0721-11 · Lifestar Pharma LLC · $0.13397 per EA · eff. 2026-09-23 filed
- 70954-0034-30 · ANI Pharmaceuticals, Inc. · $0.13397 per EA · eff. 2026-09-23 filed
- 71930-0009-12 · Eywa Pharma Inc · $0.13397 per EA · eff. 2026-09-23 filed
- 72578-0150-01 · Viona Pharmaceuticals Inc · $0.13397 per EA · eff. 2026-09-23 filed
- 72888-0048-01 · Advagen Pharma Ltd · $0.13397 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
2 other products in the NADAC file share the FDA nonproprietary name acetazolamide with ACETAZOLAMIDE 250 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ACETAZOLAMIDE 125 MG TABLET | $0.09649 per EA filed | $0.6079 per EA filed |
| ACETAZOLAMIDE 250 MG TABLET this page | $0.13397 per EA filed | $0.6079 per EA filed |
| ACETAZOLAMIDE ER 500 MG CAP | $0.28822 per EA filed | $0.77281 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 13 NDCs’ NADAC prices is $0.13397 per EA filed.
Of the 4 other products in FDA’s Carbonic Anhydrase Inhibitor class priced per EA, 3 have a higher middle NADAC price and 1 a lower one. The one in the middle is ACETAZOLAMIDE ER 500 MG CAP, at $0.28822 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $18.24 for 30 tablets, at an average of $0.6079 per EA in 2024 (2024-01-01 to 2024-12-31) for “Acetazolamide”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 246,007 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for ACETAZOLAMIDE 250 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Acetazolamide / Acetazolamide: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
Related pages
Its pharmacologic class
Related in the same class
- DORZOLAMIDE-TIMOLOL EYE DROPS
- DORZOLAMIDE HCL 2% EYE DROPS
- SIMBRINZA 1%-0.2% EYE DROP
- BRINZOLAMIDE 1% EYE DROPS