BEPOTASTINE 1.5% EYE DROP

What it is

BEPOTASTINE 1.5% EYE DROP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “bepotastine besilate” and “bepotastine besilate ophthalmic solution 1.5%”, as its NDCs’ listings variously write the nonproprietary name.

FDA gives its dosage form as “solution/ drops” and “solution” and its route as ophthalmic.

FDA lists 5 labelers (the companies named on the label) for its NDCs, among them Mylan Pharmaceuticals Inc., Bausch & Lomb Incorporated and Alembic Pharmaceuticals Inc.

FDA’s Established Pharmacologic Class for it is Histamine-1 Receptor Antagonist.

The NADAC file of 2026-10-14 prices it under 10 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $8.29 – $10.49 for 1 mL, depending on the NDC ($8.28568 to $10.48665 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

What NADAC measures · NADAC explanation codes

The 5 labelers

Other strengths, forms and brands

1 other product in the NADAC file shares an FDA nonproprietary name with BEPOTASTINE 1.5% EYE DROP.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-03-18, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 10 NDCs’ NADAC prices is $8.28568 per ML filed.

Of the 46 other products in FDA’s Histamine-1 Receptor Antagonist class priced per ML, 1 has a higher middle NADAC price and 45 a lower one. The one in the middle is ITCH RELIEF 2%-0.1% SPRAY, at $0.04712 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $21.70 for 1 mL, at an average of $21.69584 per ML in 2024 (2024-01-01 to 2024-12-31) for “Bepotastine Besilate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 59,528 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
• Which NDC (the 11-digit number on the package) is this? Pharmacies pay $8.28568 to $10.48665 per ML for this product, depending on the NDC.
• How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.